Bioactivity of an Experimental Dental Implant with Anodized Surface

Author:

Villaça-Carvalho Maria Fernanda Lima,de Araújo Juliani Caroline RibeiroORCID,Beraldo Juliana Mariano,Prado Renata Falchete do,Moraes Mari Eli Leonelli de,Manhães Junior Luiz Roberto Coutinho,Codaro Eduardo Norberto,Acciari Heloisa Andrea,Machado João Paulo Barros,Regone Natal Nerímio,Lobo Anderson Oliveira,Marciano Fernanda Roberta,Vasconcellos Luana Marotta Reis de

Abstract

Background: Several studies proved that anodic oxidation improves osseointegration. This study aimed to optimize osseointegration through anodization in dental implants, obtaining anatase phase and controlled nanotopography. Methods: The division of the groups with 60 titanium implants was: control (CG); sandblasted (SG); anodized (AG): anodized pulsed current (duty cycle 30%, 30 V, 0.2 A and 1000 Hz). Before surgery, surface characterization was performed using Atomic Force Microscopy (AFM), Scanning Electron Microscopy (SEM), X-ray Dispersive Energy Spectroscopy (EDS) and Raman Spectroscopy. For in vivo tests, 10 New Zealand white rabbits received an implant from each group. The sacrifice period was 2 and 6 weeks (n = 5) and the specimens were subjected to computed microtomography (μCT) and reverse torque test. Results: AFM and SEM demonstrated a particular nanotopography on the surface in AG; the anatase phase was proved by Raman spectroscopy. In the μCT and in the reverse torque test, the AG group presented better results than the other groups. Conclusion: The chemical composition and structure of the TiO2 film were positively affected by the anodizing technique, intensifying the biological characteristics in osseointegration.

Funder

Fundação de Amparo à Pesquisa do Estado de São Paulo

Publisher

MDPI AG

Subject

Biomedical Engineering,Biomaterials

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