Affiliation:
1. School of Biomedical Engineering, Faculty of Medicine, Dalian University of Technology, Dalian 116024, China
2. Liaoning Key Lab of Integrated Circuit and Biomedical Electronic System, Dalian University of Technology, Dalian 116024, China
Abstract
In this work, silver nanoparticles (AgNPs)/reduced graphene oxide (rGO) nanocomposites were electrodeposited on glassy carbon electrodes (GCE) to construct electrochemical sensors for the detection of hydrogen peroxide (H2O2) and dopamine (DA). The AgNPs were synthesized on graphene oxide (GO) by the hydrothermal method, followed by the reduction of the GO during the electrodeposition process, resulting in the formation of the nanocomposites on the surface of the electrodes. The generation of AgNPs on the graphene sheets was verified by scanning electron microscopy (SEM) and electrochemical impedance spectroscopy (EIS). The AgNPs/rGO/GCE showed a linear response to H2O2 in the range of 5 μM to 620 μM, with a sensitivity of 49 μA mM−1cm−2 and a limit of detection (LOD) of 3.19 μA. The linear response of the AgNPs/rGO/GCE to DA ranged from 1 μM to 276 μM, the sensitivity was 7.86 μA mM−1cm−2, and the LOD was 0.18 μM. Furthermore, DA and H2O2 were detected simultaneously in the same solution without interferences, and the sensors displayed good stability over time. The preparation method for the sensors is relatively eco-friendly, convenient, and efficient, exhibiting great potential for sensitive detection of DA and H2O2.
Funder
National Key R&D Program of China
Fundamental Research Funds for the Central Universities
Subject
Electrical and Electronic Engineering,Biochemistry,Instrumentation,Atomic and Molecular Physics, and Optics,Analytical Chemistry