Silicon-Based Scaffold for Wound Healing Skin Regeneration Applications: A Concise Review

Author:

Zulkiflee IzzatORCID,Masri Syafira,Zawani MazlanORCID,Salleh AtiqahORCID,Amirrah Ibrahim NorORCID,Wee Mohd Farhanulhakim Mohd RazipORCID,Yusop Salma MohamadORCID,Fauzi Mh BusraORCID

Abstract

Silicon has made its breakthrough in various industries, including clinical and biomedical applications. Silicon-based biomaterials that were fabricated into various types of scaffolds may attract interest due to their highly favorable properties covering their excellent biocompatibility, high surface area, mechanical strength, and selectivity depending on their application including film, hydrogel, nanoparticles, and so on. Silicon-based materials have also shown exciting results involving cell culture, cell growth, as well as tissue engineering. In this article, a simple review compromising the evaluation of silicon’s unique properties has been discussed and followed by the application of the silicone-based product in future perspectives in biomedical fields. The review goals are to widen and inspire broader interest in silicone-based materials in wound healing research.

Funder

Faculty of Medicine, Universiti Kebangsaan Malaysia under the Geran Fundamental Fakulti Perubatan

Publisher

MDPI AG

Subject

Polymers and Plastics,General Chemistry

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