3D Cultures for Modelling the Microenvironment: Current Research Trends and Applications

Author:

Gaetani Roberto1ORCID,Chimenti Isotta23ORCID

Affiliation:

1. Department of Molecular Medicine, Faculty of Pharmacy and Medicine, Sapienza University of Rome, 00185 Rome, Italy

2. Department of Medical and Surgical Sciences and Biotechnology, Faculty of Pharmacy and Medicine, Sapienza University of Rome, 04100 Latina, Italy

3. Mediterranea Cardiocentro, 80122 Naples, Italy

Abstract

The importance of 3D culture systems for drug screening or physio-pathological models has exponentially increased in recent years [...]

Funder

Sapienza University of Rome

Italian Health Ministry

Publisher

MDPI AG

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Spectroscopy,Molecular Biology,General Medicine,Catalysis

Reference19 articles.

1. Modeling Physiological Events in 2D vs. 3D Cell Culture;Duval;Physiology,2017

2. 3D bioprinting of tissues and organs;Murphy;Nat. Biotechnol.,2014

3. Cardiac Mechanoperception: A Life-Long Story from Early Beats to Aging and Failure;Pesce;Stem Cells Dev.,2017

4. (2023, May 25). Available online: https://www.cbo.gov/publication/57126.

5. Human organs-on-chips for disease modelling, drug development and personalized medicine;Ingber;Nat. Rev. Genet.,2022

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