Affiliation:
1. Department of Chemistry, Alexandru Ioan Cuza University of Iasi, 11 Carol I Blvd., 700506 Iasi, Romania
Abstract
The aim of this review is to highlight the chemopreventive properties of hydroxy-substituted natural and synthetic chalcones along with a number of their analogs. These products display various biological activities, and have many applications against various diseases. Antioxidant and anti-inflammatory properties of chalcones bearing hydroxy substituents are underlined. The influence of hydroxy substituents located on ring A, B, or both are systematized according to the exhibited biological properties.
Subject
Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Spectroscopy,Molecular Biology,General Medicine,Catalysis
Reference111 articles.
1. Diverse Molecular Targets for Chalcones with Varied Bioactivities;Zhou;Med. Chem.,2015
2. Trends in utilization of the pharmacological potential of chalcones;Batovska;Curr. Clin. Pharmacol.,2010
3. Recent developments in biological activities of chalcones: A mini review;Singh;Eur. J. Med. Chem.,2014
4. Rajendran, G., Bhanu, D., Aruchamy, B., Ramani, P., Pandurangan, N., Bobba, K.N., Oh, E.J., Chung, H.Y., Gangadaran, P., and Ahn, B.-C. (2022). Chalcone: A Promising Bioactive Scaffold in Medicinal Chemistry. Pharmaceuticals, 15.
5. Dramatic activity enhancement of natural phosphate catalyst by lithium nitrate. An efficient synthesis of chalcones;Sebti;Catal. Commun.,2002
Cited by
10 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献