Towards Real-Time Hyperspectral Multi-Image Super-Resolution Reconstruction Applied to Histological Samples

Author:

Urbina Ortega Carlos123ORCID,Quevedo Gutiérrez Eduardo2ORCID,Quintana Laura2ORCID,Ortega Samuel24ORCID,Fabelo Himar25ORCID,Santos Falcón Lucana12,Marrero Callico Gustavo2ORCID

Affiliation:

1. European Space Agency, TEC-ED, 2201 AZ Noordwijk, The Netherlands

2. Research Institute for Applied Microelectronics (IUMA), University of Las Palmas de Gran Canaria (ULPGC), 35017 Las Palmas de Gran Canaria, Spain

3. Telespazio Belgium SRL, Huygensstraat 34, 2201 DK Noordwijk, The Netherlands

4. Nofima—Norwegian Institute of Food Fisheries and Aquaculture Research, NO-9291 Tromsø, Norway

5. Fundación Instituto de Investigación Sanitaria de Canarias (FIISC), 35017 Gran Canaria, Spain

Abstract

Hyperspectral Imaging (HSI) is increasingly adopted in medical applications for the usefulness of understanding the spectral signature of specific organic and non-organic elements. The acquisition of such images is a complex task, and the commercial sensors that can measure such images is scarce down to the point that some of them have limited spatial resolution in the bands of interest. This work proposes an approach to enhance the spatial resolution of hyperspectral histology samples using super-resolution. As the data volume associated to HSI has always been an inconvenience for the image processing in practical terms, this work proposes a relatively low computationally intensive algorithm. Using multiple images of the same scene taken in a controlled environment (hyperspectral microscopic system) with sub-pixel shifts between them, the proposed algorithm can effectively enhance the spatial resolution of the sensor while maintaining the spectral signature of the pixels, competing in performance with other state-of-the-art super-resolution techniques, and paving the way towards its use in real-time applications.

Publisher

MDPI AG

Subject

Electrical and Electronic Engineering,Biochemistry,Instrumentation,Atomic and Molecular Physics, and Optics,Analytical Chemistry

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