Analog Filters Design for Improving Precision in Proton Sound Detectors

Author:

Vallicelli Elia ArturoORCID,De Matteis MarcelloORCID

Abstract

This paper analyzes how to improve the precision of ionoacoustic proton range verification by optimizing the analog signal processing stages with particular emphasis on analog filters. The ionoacoustic technique allows one to spatially detect the proton beam penetration depth/range in a water absorber, with interesting possible applications in real-time beam monitoring during hadron therapy treatments. The state of the art uses nonoptimized detectors that have low signal quality and thus require a higher total dose, which is not compatible with clinical applications. For these reasons, a comprehensive analysis of acoustic signal bandwidth, signal-to-noise-ratio and noise power/bandwidth will be presented. The correlation between these signal-quality parameters with maximum achievable proton range measurement precision will be discussed. In particular, the use of an optimized analog filter allows one to decrease the dose required to achieve a given precision by as much as 98.4% compared to a nonoptimized filter approach.

Funder

Instituto Nazionale di Fisica Nucleare

Publisher

MDPI AG

Subject

Electrical and Electronic Engineering

Cited by 7 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. A 7.69 ENOB, $161\mu W$ SAR ADC in 28nm CMOS for Proton Sound Detectors;2024 19th Conference on Ph.D Research in Microelectronics and Electronics (PRIME);2024-06-09

2. 50-Channel Ionoacoustic Sensor for 60 MeV Proton Beam Characterization in Hadron Therapy Applications;SN Computer Science;2024-01-20

3. Proton Sound Detector for beam range/dose measurement in FLASH hadron therapy;Journal of Instrumentation;2022-07-01

4. paMELA - Photoacoustic Melanoma Detector Design for Real-Time Imaging of Melanin with 18 db SNR and 10 μm Precision;Proceedings of the 15th International Joint Conference on Biomedical Engineering Systems and Technologies;2022

5. 2.6-MHz 4.9-mW 37.5 dB-SNR Analog Front-End for Proton Sound Detectors in 28 nm CMOS;2021 28th IEEE International Conference on Electronics, Circuits, and Systems (ICECS);2021-11-28

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