High Prevalence of Bovine Cardiac Cysticercosis in Upper Egypt: An Epidemiological and Histopathological Study-Reference-Cited by-同舟云学术

High Prevalence of Bovine Cardiac Cysticercosis in Upper Egypt: An Epidemiological and Histopathological Study

Published:2024-01-03 Issue:1 Volume:14 Page:158
ISSN:2076-2615
Container-title:Animals
language:en
Short-container-title:Animals

Author:

Anwar Fatma A. S.¹,Negm Eman A.²³^ORCID,Abdelhaseib Maha⁴^ORCID,Abdel-maksoud Fatma M.⁵⁶^ORCID,Mohammed Ahmed A.⁷,Mohamed Sara Abdel-Aal⁸,Gareh Ahmed⁹^ORCID,Elbarbary Nady Khairy¹⁰,El-khadragy Manal F.¹¹,Hassan Ehssan Ahmed¹²¹³,Elmahallawy Ehab Kotb¹⁴¹⁵^ORCID

Affiliation:

1. Department of Zoology, Faculty of Science, Assiut University, Assiut 71526, Egypt

2. Department of Physiology, Faculty of Veterinary Medicine, Assiut University, Assiut 71526, Egypt

3. Department of Animal Physiology and Biochemistry, School of Veterinary Medicine, Badr University in Assiut, New Nasser City, Assiut 11829, Egypt

4. Department of Food Hygiene, Faculty of Veterinary Medicine, Assiut University, Assiut 71526, Egypt

5. Department of Anatomy and Embryology, Faculty of Veterinary Medicine, Assiut University, Assiut 71526, Egypt

6. Department of Anatomy and Embryology, Faculty of Veterinary Medicine, Sphinx University, Assiut 71515, Egypt

7. Department of Animal and Poultry Behavior and Management, Faculty of Veterinary Medicine, Assiut University, Assiut 71526, Egypt

8. Department of Parasitology, Faculty of Veterinary Medicine, Assiut University, Assiut 71526, Egypt

9. Department of Parasitology, Faculty of Veterinary Medicine, Aswan University, Aswan 24101, Egypt

10. Department of Food Hygiene, Faculty of Veterinary Medicine, Aswan University, Aswan 81528, Egypt

11. Department of Biology, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia

12. Department of Biology, College of Science and Humanities in Alkharj, Prince Sattam Bin Abdulaziz University, Alkharj 11942, Saudi Arabia

13. Department of Zoology, Faculty of Science, Suez Canal University, El-Sheikh Zayed, Ismailia 41522, Egypt

14. Departamento de Sanidad Animal, Grupo de Investigación en Sanidad Animal y Zoonosis (GISAZ), Facultad de Veterinaria, Universidad de Córdoba, E-14071 Córdoba, Spain

15. Department of Zoonoses, Faculty of Veterinary Medicine, Sohag University, Sohag 82524, Egypt

Abstract

Bovine cysticercosis is categorized as a serious parasitic zoonotic infestation. The infection is mainly caused by the tapeworm Taenia saginata, which infects cattle and humans. The larval stage, Cysticercus bovis (C. bovis), is found in the skeletal and cardiac muscles of infected cattle. Despite its potential public health concern, few studies have been conducted on cardiac cysticercosis in Upper Egypt. This study investigates the prevalence, epidemiology, and impact of cardiac cysticercosis in Upper Egypt, emphasizing how histopathological changes in cardiac muscle and physiological parameters might be associated with the infection. From December 2022 to October 2023, a total of 941 animals from Assiut province, Upper Egypt, were slaughtered and their cardiac muscles were examined for the presence of C. bovis. Cysts were classified as viable or degenerated through macroscopic inspection. The overall prevalence of C. bovis infected hearts made up 10.8% of the total examined. The highest prevalence rate was in the summer season followed by spring; winter had the lowest infections. The histopathological examination of infected tissues revealed immune cell infiltration around Cysticercus-infected areas. Additionally, Bax immunostaining demonstrated the apoptotic effect of cysticercosis. Regarding the measured physiological parameters, there were non-significant changes in plasma levels of total protein and albumin in cattle infected with cysticercosis compared with control animals. Moreover, there was a significant decrease in total antioxidant capacity (TAC) combined with a significant increase in lipid peroxide (Malondialdehyde) (MDA), troponin T, and lactate dehydrogenase (LDH) activity in infected animals. The present work documented a set of epidemiological and pathological findings, revealing that C. bovis is a potentially harmful parasite and can cause significant health problems in both cattle and humans.

Funder

Princess Nourah bint Abdulrahman University

Publisher

MDPI AG

Subject

General Veterinary,Animal Science and Zoology

Link

https://www.mdpi.com/2076-2615/14/1/158/pdf

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