Farnesol-Containing Macromolecular Systems for Antibiofilm Strategies

Abstract

Farnesol is a natural sesquiterpenoid and an interesting quorum-sensing molecule. Its insolubility in water is the biggest obstacle to its application for bacterial biofilm treatments since it compromises the bioavailability. Recently, an increasing interest in farnesol encapsulation or loading in polymeric materials may be noted due to the prolonged action of the active macromolecular systems. In this short review, we present an overview of methods leading to improved interactions between farnesol and microbial biofilms.