Author:
Chang Xiaoran,Lin Qian,Zhang Qun,Hu Junying,Tursun Gulbahar,Deng Yingrui,Guo Chunguang,Wang Xinping
Abstract
Here, we report the characterization of 13 novel caprine/ovine enterovirus strains isolated from different regions in China during 2016–2021. Immunoperoxidase monolayer assay showed that these viral strains shared strong cross-reaction with the previously reported caprine enterovirus CEV-JL14. Alignment analysis of the complete nucleotide sequences revealed 79.2%–87.8% and 75.0%–76.7% sequence identity of these novel caprine enterovirus strains to CEV-JL14 and TB4-OEV, respectively. Phylogenetic analyses clustered these novel strains to EV-G based on the amino acid sequences of P1 and 2C+3CD. Moreover, phylogenetic analysis of these caprine enterovirus strains identified three new EV-G types using VP1 sequences. These results demonstrate the genetic variations and the evolution of caprine enterovirus.
Funder
National Natural Science Foundation of China
National Key Research & Development Program
Subject
Virology,Infectious Diseases
Cited by
5 articles.
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