Recent Trends in Hydroxyapatite Supplementation for Osteoregenerative Purposes-Reference-Cited by-同舟云学术

Recent Trends in Hydroxyapatite Supplementation for Osteoregenerative Purposes

Published:2023-02-03 Issue:3 Volume:16 Page:1303
ISSN:1996-1944
Container-title:Materials
language:en
Short-container-title:Materials

Author:

Zastulka Ana¹,Clichici Simona¹^ORCID,Tomoaia-Cotisel Maria²³,Mocanu Aurora²,Roman Cecilia⁴,Olteanu Cristian-Doru⁵,Culic Bogdan⁶,Mocan Teodora¹⁷

Affiliation:

1. Physiology Department, Iuliu Hatieganu University of Medicine and Pharmacy, 1 Clinicilor Street, 400006 Cluj-Napoca, Romania

2. Department of Chemical Engineering, Faculty of Chemistry and Chemical Engineering, Research Center in Physical Chemistry, Babes-Bolyai University of Cluj-Napoca, 11 Arany Janos Str., 400028 Cluj-Napoca, Romania

3. Academy of Romanian Scientists, 3 Ilfov Str., 050044 Bucharest, Romania

4. INCDO-INOE 2000, Research Institute for Analytical Instrumentation, 400296 Cluj-Napoca, Romania

5. Orthodontic Department, Iuliu Hatieganu University of Medicine and Pharmacy, 31 Avram Iancu Street, 400083 Cluj-Napoca, Romania

6. Department of Prosthetic Dentistry and Dental Materials, Iuliu Hatieganu University of Medicine and Pharmacy, 32 Clinicilor Street, 400012 Cluj-Napoca, Romania

7. Nanomedicine Department, Regional Institute of Gastroenterology and Hepatology Cluj-Napoca, 5 Constanta Street, 400158 Cluj-Napoca, Romania

Abstract

Bone regeneration has gained attention in the biomedical field, which has led to the development of materials and synthesis methods meant to improve osseointegration and cellular bone activity. The properties of hydroxyapatite, a type of calcium phosphate, have been researched to determine its advantages for bone tissue engineering, particularly its biocompatibility and ability to interact with bone cells. Recently, the advantages of utilizing nanomolecules of hydroxyapatite, combined with various substances, in order to enhance and combine their characteristics, have been reported in the literature. This review will outline the cellular and molecular roles of hydroxypatite, its interactions with bone cells, and its nano-combinations with various ions and natural products and their effects on bone growth, development, and bone repair.

Funder

Romanian National Authority for Scientific Research and Innovation

Publisher

MDPI AG

Subject

General Materials Science

Link

https://www.mdpi.com/1996-1944/16/3/1303/pdf

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