Polyphenols: Natural Preservatives with Promising Applications in Food, Cosmetics and Pharma Industries; Problems and Toxicity Associated with Synthetic Preservatives; Impact of Misleading Advertisements; Recent Trends in Preservation and Legislation

Author:

Rathee Priyanka1ORCID,Sehrawat Renu2,Rathee Pooja3,Khatkar Anurag3,Akkol Esra Küpeli4ORCID,Khatkar Sarita5,Redhu Neelam6,Türkcanoğlu Gizem4,Sobarzo-Sánchez Eduardo78ORCID

Affiliation:

1. Faculty of Pharmaceutical Sciences, Baba Mastnath University, Rohtak 124021, India

2. School of Medical and Allied Sciences, K.R. Mangalam University, Gurugram 122103, India

3. Department of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak 124001, India

4. Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, Ankara 06330, Turkey

5. Vaish Institute of Pharmaceutical Education and Research, Rohtak 124001, India

6. Department of Microbiology, Maharshi Dayanand University, Rohtak 124001, India

7. Instituto de Investigación y Postgrado, Facultad de Ciencias de la Salud, Universidad Central de Chile, Santiago 8330507, Chile

8. Department of Organic Chemistry, Faculty of Pharmacy, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain

Abstract

The global market of food, cosmetics, and pharmaceutical products requires continuous tracking of harmful ingredients and microbial contamination for the sake of the safety of both products and consumers as these products greatly dominate the consumer’s health, directly or indirectly. The existence, survival, and growth of microorganisms in the product may lead to physicochemical degradation or spoilage and may infect the consumer at another end. It has become a challenge for industries to produce a product that is safe, self-stable, and has high nutritional value, as many factors such as physical, chemical, enzymatic, or microbial activities are responsible for causing spoilage to the product within the due course of time. Thus, preservatives are added to retain the virtue of the product to ensure its safety for the consumer. Nowadays, the use of synthetic/artificial preservatives has become common and has not been widely accepted by consumers as they are aware of the fact that exposure to preservatives can lead to adverse effects on health, which is a major area of concern for researchers. Naturally occurring phenolic compounds appear to be extensively used as bio-preservatives to prolong the shelf life of the finished product. Based on the convincing shreds of evidence reported in the literature, it is suggested that phenolic compounds and their derivatives have massive potential to be investigated for the development of new moieties and are proven to be promising drug molecules. The objective of this article is to provide an overview of the significant role of phenolic compounds and their derivatives in the preservation of perishable products from microbial attack due to their exclusive antioxidant and free radical scavenging properties and the problems associated with the use of synthetic preservatives in pharmaceutical products. This article also analyzes the recent trends in preservation along with technical norms that regulate the food, cosmetic, and pharmaceutical products in the developing countries.

Publisher

MDPI AG

Subject

General Materials Science

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