A Green Light to Switch on Genes: Revisiting Trithorax on Plants

Author:

Ornelas-Ayala Diego,Cortés-Quiñones CarlosORCID,Olvera-Herrera José,García-Ponce BereniceORCID,Garay-Arroyo AdrianaORCID,Álvarez-Buylla Elena R.,Sanchez Maria de la PazORCID

Abstract

The Trithorax Group (TrxG) is a highly conserved multiprotein activation complex, initially defined by its antagonistic activity with the PcG repressor complex. TrxG regulates transcriptional activation by the deposition of H3K4me3 and H3K36me3 marks. According to the function and evolutionary origin, several proteins have been defined as TrxG in plants; nevertheless, little is known about their interactions and if they can form TrxG complexes. Recent evidence suggests the existence of new TrxG components as well as new interactions of some TrxG complexes that may be acting in specific tissues in plants. In this review, we bring together the latest research on the topic, exploring the interactions and roles of TrxG proteins at different developmental stages, required for the fine-tuned transcriptional activation of genes at the right time and place. Shedding light on the molecular mechanism by which TrxG is recruited and regulates transcription.

Funder

UNAM-DGAPA-PAPIIT

CONACyT

Publisher

MDPI AG

Subject

Plant Science,Ecology,Ecology, Evolution, Behavior and Systematics

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