Lack of Biological Plausibility and Major Methodological Issues Cast Doubt on the Association between Aspartame and Autism. Comment on Fowler et al. Daily Early-Life Exposures to Diet Soda and Aspartame Are Associated with Autism in Males: A Case-Control Study. Nutrients 2023, 15, 3772-Reference-Cited by-同舟云学术

Lack of Biological Plausibility and Major Methodological Issues Cast Doubt on the Association between Aspartame and Autism. Comment on Fowler et al. Daily Early-Life Exposures to Diet Soda and Aspartame Are Associated with Autism in Males: A Case-Control Study. Nutrients 2023, 15, 3772

Published:2024-02-28 Issue:5 Volume:16 Page:675
ISSN:2072-6643
Container-title:Nutrients
language:en
Short-container-title:Nutrients

Author:

Ayoub-Charette Sabrina¹²^ORCID,Khan Tauseef Ahmad¹²^ORCID,Chiavaroli Laura¹²³^ORCID,Magnuson Bernadene A.⁴,Sievenpiper John L.¹²³⁵⁶

Affiliation:

1. Department of Nutritional Sciences, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada

2. Toronto 3D Knowledge Synthesis and Clinical Trials Unit, Clinical Nutrition and Risk Factor Modification Centre, St. Michael’s Hospital, Toronto, ON M5C 2T2, Canada

3. Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, ON M5B 1T8, Canada

4. Health Science Consultants Inc., Collingwood, ON L9Y 0Z5, Canada

5. Division of Endocrinology and Metabolism, Department of Medicine, St. Michael’s Hospital, Toronto, ON M5C 2T2, Canada

6. Department of Medicine, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada

Abstract

The case–control study by Fowler et al [...]

Funder

Canadian Institutes of Health Research

Toronto 3D New Investigator award

Publisher

MDPI AG

Link

https://www.mdpi.com/2072-6643/16/5/675/pdf

Reference8 articles.

1. Fowler, S.P., Gimeno Ruiz de Porras, D., Swartz, M.D., Stigler Granados, P., Heilbrun, L.P., and Palmer, R.F. (2023). Daily Early-Life Exposures to Diet Soda and Aspartame Are Associated with Autism in Males: A Case-Control Study. Nutrients, 15.

2. Maternal dietary factors and the risk of autism spectrum disorders: A systematic review of existing evidence;Zhong;Autism Res.,2020

3. Aspartame: A safety evaluation based on current use levels, regulations, and toxicological and epidemiological studies;Magnuson;Crit. Rev. Toxicol.,2007

4. (2023, November 16). Joint FAO/WHO Expert Committee on Food Additives (JECFA). Aspartame (WHO Food Additives Series 16). Available online: https://inchem.org/documents/jecfa/jecmono/v16je03.htm.

5. Non-nutritive sweeteners in human amniotic fluid and cord blood: Evidence of transplacental fetal exposure;Halasa;Am. J. Perinatol.,2023

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Reply to Ayoub-Charette et al. Lack of Biological Plausibility and Major Methodological Issues Cast Doubt on the Association between Aspartame and Autism. Comment on “Fowler et al. Daily Early-Life Exposures to Diet Soda and Aspartame Are Associated with Autism in Males: A Case-Control Study. Nutrients 2023, 15, 3772”;Nutrients;2024-02-28