Epizootic Haemorrhagic Disease Virus Serotype 8 in Tunisia, 2021

Author:

Sghaier Soufien,Sailleau Corinne,Marcacci MauriliaORCID,Thabet Sarah,Curini ValentinaORCID,Ben Hassine Thameur,Teodori Liana,Portanti OttavioORCID,Hammami Salah,Jurisic Lucija,Spedicato MassimoORCID,Postic LydieORCID,Gazani Ines,Ben Osman Raja,Zientara Stephan,Bréard EmmanuelORCID,Calistri PaoloORCID,Richt Jürgen A.ORCID,Holmes Edward C.ORCID,Savini Giovanni,Di Giallonardo FrancescaORCID,Lorusso AlessioORCID

Abstract

Epizootic haemorrhagic disease (EHD) is a Culicoides-borne viral disease caused by the epizootic haemorrhagic disease virus (EHDV) associated with clinical manifestations in domestic and wild ruminants, primarily white-tailed deer (Odocoileus virginianus) and cattle (Bos taurus). In late September 2021, EHDV was reported in cattle farms in central/western Tunisia. It rapidly spread throughout the country with more than 200 confirmed outbreaks. We applied a combination of classical and molecular techniques to characterize the causative virus as a member of the serotype EHDV-8. This is the first evidence of EHDV- 8 circulation since 1982 when the prototype EHDV-8 strain was isolated in Australia. This work highlights the urgent need for vaccines for a range of EHDV serotypes.

Funder

Prima Foundation

Ricerca Finalizzata

European Union’s Horizon 2020 Research and Innovation program

MCP Core of the Center of Emerging and Zoonotic Infectious Diseases (CEZID) from National Institute of General Medical Sciences

Publisher

MDPI AG

Subject

Virology,Infectious Diseases

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