Post-COVID Kawasaki-like Multisystem Inflammatory Syndrome Complicated by Herpes Simplex Virus-1 in a Two-Year-Old Child-Reference-Cited by-同舟云学术

Post-COVID Kawasaki-like Multisystem Inflammatory Syndrome Complicated by Herpes Simplex Virus-1 in a Two-Year-Old Child

Published:2023-09-11 Issue:3 Volume:3 Page:224-231
ISSN:2673-6179
Container-title:Dermato
language:en
Short-container-title:Dermato

Author:

Hodson Emma L.¹,Salem Iman¹,Bradley Katherine E.²,Okorie Chiamaka L.²^ORCID,Marka Arthur¹,Abraham Nigel D.³,Pace Nicole C.¹²³,Dagrosa Alicia T.¹²,Ratts Ryan C.⁴⁵,Mann Julianne A.¹²³

Affiliation:

1. Department of Dermatology, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03766, USA

2. Geisel School of Medicine, Dartmouth College, Hanover, NH 03755, USA

3. Department of Pediatrics, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03766, USA

4. Department of Medicine, Section of Hospital Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03766, USA

5. Department of Pediatrics, Section of Pediatric Hospital Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03766, USA

Abstract

Multisystem inflammatory syndrome in children (MIS-C) is a rare, systemic inflammation following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We report a case of a 2-year-old male who presented with an exanthem and aberrant laboratory markers, mimicking Kawasaki disease but failing to meet the full diagnostic criteria. His course was further complicated by herpes Simplex Virus-1 (HSV-1) stomatitis.

Publisher

MDPI AG

Subject

General Medicine

Link

https://www.mdpi.com/2673-6179/3/3/17/pdf

Reference19 articles.

1. The potential threat of multisystem inflammatory syndrome in children during the COVID-19 pandemic;Rothan;Pediatr. Allergy Immunol.,2021

2. Ramaswamy, A., Brodsky, N.N., Sumida, T.S., Comi, M., Asashima, H., Hoehn, K.B., Li, N., Liu, Y., Shah, A., and Ravindra, N.G. (2021). Post-infectious inflammatory disease in MIS-C features elevated cytotoxicity signatures and autoreactivity that correlates with severity. medRxiv, 2020-12.

3. Interpreting diagnostic tests for SARS-CoV-2;Sethuraman;JAMA,2020

4. Overexpression of the SARS-CoV-2 receptor ACE2 is induced by cigarette smoke in bronchial and alveolar epithelia;Liu;J. Pathol.,2021

5. Diagnosis of Kawasaki disease;Singh;Int. J. Rheum. Dis.,2018