Exploring the Multifactorial Landscape of Penile Cancer: A Comprehensive Analysis of Risk Factors-Reference-Cited by-同舟云学术

Exploring the Multifactorial Landscape of Penile Cancer: A Comprehensive Analysis of Risk Factors

Published:2024-08-16 Issue:16 Volume:14 Page:1790
ISSN:2075-4418
Container-title:Diagnostics
language:en
Short-container-title:Diagnostics

Author:

Amicuzi Ugo¹,Grillo Marco²,Stizzo Marco³,Olivetta Michelangelo⁴^ORCID,Tammaro Simone⁵^ORCID,Napolitano Luigi⁵^ORCID,Reccia Pasquale⁶,De Luca Luigi⁷,Rubinacci Andrea⁵,Della Rosa Giampiero⁵,Lecce Arturo⁵,Coppola Paola⁵,Papi Salvatore⁵,Trama Francesco⁸^ORCID,Romano Lorenzo⁵,Sciorio Carmine⁹,Spirito Lorenzo³^ORCID,Crocetto Felice⁵^ORCID,Manfredi Celeste³^ORCID,Del Giudice Francesco¹⁰^ORCID,Ferro Matteo¹¹^ORCID,Rocco Bernardo¹¹,Tataru Octavian Sabin¹²,Balsamo Raffaele⁶,Lucarelli Giuseppe¹³^ORCID,Del Biondo Dario²¹⁴,Barone Biagio¹⁴^ORCID

Affiliation:

1. Division of Urology, Department of Surgical Sciences, AORN Sant’Anna e San Sebastiano, 81100 Caserta, Italy

2. Department of Urology, Ospedale del Mare, ASL NA1 Centro, 80147 Naples, Italy

3. Urology Unit, Department of Woman, Child and General and Specialized Surgery, University of Campania Luigi Vanvitelli, 80131 Naples, Italy

4. Urology Unit, Gaetano Fucito Hospital, AOU San Giovanni di Dio e Ruggi d’Aragona, 84085 Mercato San Severino, Italy

5. Department of Neurosciences and Reproductive Sciences and Odontostomatology, University of Naples Federico II, 80131 Naples, Italy

6. Urology Unit, AORN Ospedali dei Colli, Monaldi Hospital, 80131 Naples, Italy

7. Division of Urology, Department of Surgical Multispecialty, AORN Antonio Cardarelli, 80131 Naples, Italy

8. Urology Complex Unit, ASL Napoli 2 Nord ‘Santa Maria delle Grazie’ Hospital, 80078 Pozzuoli, Italy

9. Urology Unit, ASST Ospedale Manzoni, 23900 Lecco, Italy

10. Department of Urology, University Sapienza, 00185 Rome, Italy

11. 2nd Unit of Urology, Department of Health Science, University of Milan, ASST Santi Paolo and Carlo, Via A. Di Rudini 8, 20142 Milan, Italy

12. Department of Simulation Applied in Medicine, The Institution Organizing University Doctoral Studies (I.O.S.U.D.), George Emil Palade University of Medicine, Pharmacy, Sciences, and Technology from Târgu Mureș, 540142 Târgu Mureș, Romania

13. Urology, Andrology and Kidney Transplantation Unit, Department of Emergency and Organ Transplantation, University of Bari, 70124 Bari, Italy

14. Department of Urology, Ospedale San Paolo, ASL NA1 Centro, 80125 Naples, Italy

Abstract

Penile cancer, while rare, is a critical public health issue due to its profound impact on patients and the complexities of its management. The disease’s multifactorial etiology includes risk factors such as HPV infection, poor hygiene, smoking, genetic predispositions, and socioeconomic determinants. This article provides a comprehensive review and analysis of these diverse risk factors, aiming to enhance understanding of the disease’s underlying causes. By elucidating these factors, the article seeks to inform and improve prevention strategies, early detection methods, and therapeutic interventions. A nuanced grasp of the multifactorial nature of penile cancer can enable healthcare professionals to develop more effective approaches to reducing incidence rates and improving patient outcomes.

Publisher

MDPI AG

Link

https://www.mdpi.com/2075-4418/14/16/1790/pdf

Reference121 articles.

1. Epidemiologic Profile, Sexual History, Pathologic Features, and Human Papillomavirus Status of 103 Patients with Penile Carcinoma;Chaux;World J. Urol.,2013

2. Urologic Malignancies: Advances in the Analysis and Interpretation of Clinical Findings;Crocetto;Future Sci. OA,2021

3. Differences in Overall Survival of Penile Cancer Patients versus Population-based Controls;Scheipner;Int. J. Urol.,2024

4. Torres Irizarry, V.M., Paster, I.C., Ogbuji, V., Gomez, D.M., Mccormick, K., and Chipollini, J. (2024). Improving Quality of Life and Psychosocial Health for Penile Cancer Survivors: A Narrative Review. Cancers, 16.

5. Psychosocial Impact of Penile Carcinoma;Audenet;Transl. Androl. Urol.,2017