An Interpretable Approach with Explainable AI for Heart Stroke Prediction

Author:

Srinivasu Parvathaneni Naga12ORCID,Sirisha Uddagiri2ORCID,Sandeep Kotte3ORCID,Praveen S. Phani2,Maguluri Lakshmana Phaneendra4ORCID,Bikku Thulasi5

Affiliation:

1. Department of Teleinformatics Engineering, Federal University of Ceará, Fortaleza 60455-970, Brazil

2. Department of Computer Science and Engineering, Prasad V Potluri Siddhartha Institute of Technology, Vijayawada 520007, India

3. Department of Information Technology, Dhanekula Institute of Engineering & Technology, Vijayawada 521139, India

4. Department of Computer Science and Engineering, Koneru Lakshmaiah Education Foundation, Vaddeswaram, Guntur 522302, India

5. Computer Science and Engineering, Amrita School of Computing Amaravati, Amrita Vishwa Vidyapeetham, Amaravati 522503, India

Abstract

Heart strokes are a significant global health concern, profoundly affecting the wellbeing of the population. Many research endeavors have focused on developing predictive models for heart strokes using ML and DL techniques. Nevertheless, prior studies have often failed to bridge the gap between complex ML models and their interpretability in clinical contexts, leaving healthcare professionals hesitant to embrace them for critical decision-making. This research introduces a meticulously designed, effective, and easily interpretable approach for heart stroke prediction, empowered by explainable AI techniques. Our contributions include a meticulously designed model, incorporating pivotal techniques such as resampling, data leakage prevention, feature selection, and emphasizing the model’s comprehensibility for healthcare practitioners. This multifaceted approach holds the potential to significantly impact the field of healthcare by offering a reliable and understandable tool for heart stroke prediction. In our research, we harnessed the potential of the Stroke Prediction Dataset, a valuable resource containing 11 distinct attributes. Applying these techniques, including model interpretability measures such as permutation importance and explainability methods like LIME, has achieved impressive results. While permutation importance provides insights into feature importance globally, LIME complements this by offering local and instance-specific explanations. Together, they contribute to a comprehensive understanding of the Artificial Neural Network (ANN) model. The combination of these techniques not only aids in understanding the features that drive overall model performance but also helps in interpreting and validating individual predictions. The ANN model has achieved an outstanding accuracy rate of 95%.

Publisher

MDPI AG

Subject

Clinical Biochemistry

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