Gender-Specific Differences in Spinal Alignment and Muscle Power in Patients with Parkinson’s Disease

Author:

Bissolotti Luciano1,Rota Matteo2ORCID,Calza Stefano2ORCID,Romero-Morales Carlos3ORCID,Alonso-Pérez José Luís34567ORCID,López-Bueno Rubén8910ORCID,Villafañe Jorge Hugo34ORCID

Affiliation:

1. Fondazione Teresa Camplani Casa di Cura Domus Salutis, 25123 Brescia, Italy

2. Department of Molecular and Translational Medicine, University of Brescia, 25121 Brescia, Italy

3. Department of Physiotherapy, Faculty of Sport Sciences, Universidad Europea de Madrid, 28670 Villaviciosa de Odón, Spain

4. Musculoskeletal Pain and Motor Control Research Group, Faculty of Sport Sciences, Universidad Europea de Madrid, 28670 Villaviciosa de Odón, Spain

5. Musculoskeletal Pain and Motor Control Research Group, Faculty of Health Sciences, Universidad Europea de Canarias, C/Inocencio García 1, 38300 La Orotava, Canary Islands, Spain

6. Department of Physiotherapy, Faculty of Health Sciences, Universidad Europea de Canarias, 38300 Santa Cruz de Tenerife, Spain

7. Onelife Center, Multidisciplinary Pain Treatment Center, 28925 Alcorcón, Spain

8. Department of Physical Medicine and Nursing, University of Zaragoza, 50009 Zaragoza, Spain

9. National Research Centre for the Working Environment, 2100 Copenhagen, Denmark

10. Exercise Intervention for Health Research Group (EXINH-RG), Department of Physiotherapy, University of Valencia, 46100 Valencia, Spain

Abstract

Background: Parkinson’s disease (PD) is an advancing neurodegenerative disorder characterized by spinal anomalies and muscular weakness, which may restrict daily functional capacities. A gender-focused examination of these effects could provide valuable insights into customized rehabilitation strategies for both sexes. Purpose: This study investigates the influence of spinal alignment on lower-limb function during the sit-to-stand (STS) movement in patients with Parkinson’s disease compared to healthy individuals. Methods: A cross-sectional study was conducted with 43 consecutive patients with PD (25 males and 18 females; average age 73.7 ± 7.1 years) and 42 healthy controls (22 males and 20 females; average age 69.8 ± 6.0 years). Assessments included the International Physical Activity Questionnaire (IPAQ), Hoehn and Yahr staging, and measurements of vertical deviations from several spinal landmarks. Lower-limb muscle power during the STS task was evaluated using the Muscle Quality Index (MQI). Results: Both absolute (Watts) and relative (Watts/Kg) muscle power in the lower limbs were notably decreased in the PD group compared to the control group. Within the PD cohort, muscle power showed a negative relationship with age and a positive association with the degree of lumbar lordosis (PL-L3). Importantly, gender-specific analysis revealed that male patients with PD had significantly higher lower-limb muscle power compared to female patients with PD, highlighting the need for gender-tailored therapeutic approaches. Conclusions: The findings suggest that preserving lumbar lordosis is crucial for maintaining effective lower-limb muscle biomechanics in individuals with Parkinson’s disease.

Publisher

MDPI AG

Reference37 articles.

1. Joint and Skeletal Deformities in Parkinson’s Disease, Multiple System Atrophy, and Progressive Supranuclear Palsy;Ashour;Mov. Disord.,2006

2. Camptocormia in Parkinson’s Disease: Definition, Epidemiology, Pathogenesis and Treatment Modalities;Srivanitchapoom;J. Neurol. Neurosurg. Psychiatry,2016

3. Scoliosis in Patients with Parkinson’s Disease;Baik;J. Clin. Neurol.,2009

4. Postural Deformities in Parkinson’s Disease;Doherty;Lancet Neurol.,2011

5. Effects of Telemedicine for Postural Instability in Independent Patients with Parkinson’s Disease: A Literature Review;Battaglino;Top. Geriatr. Rehabil.,2023

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