Positron Emission Tomography/Computed Tomography (PET/CT)-Based, Local Consolidative Radiotherapy after Chemoimmunotherapy in Metastatic, Non-Oncogene-Addicted Non-Small-Cell Lung Cancer (NSCLC)

Author:

Angelini Lucia12ORCID,Pazos Montserrat2,Käsmann Lukas234,Manapov Farkhad234

Affiliation:

1. Department of Experimental and Clinical Biomedical Sciences, University of Florence, 50134 Florence, Italy

2. Department of Radiation Oncology, University Hospital, LMU Munich, Ziemsenstrasse 1, 80336 Munich, Germany

3. German Center for Lung Research (DZL), Comprehensive Pneumology Center Munich (CPC-M), 81377 Munich, Germany

4. German Cancer Consortium (DKTK), Partner Site Munich, 81377 Munich, Germany

Abstract

The optimal sequence of chemo/immuno- and radiotherapy (RT) in metastatic non-small-cell lung cancer (NSCLC) remains challenging. Here, we describe the case of a 58-year-old female patient with an initially metastasized NSCLC obtaining local and distance durable response after chemo-immunotherapy and local RT associated with immunotherapy maintenance. Our experience offers a valuable perspective in choosing how to combine therapies to ensure the longest possible response in patients with estimated poor prognosis.

Publisher

MDPI AG

Subject

Clinical Biochemistry

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