Renal Biomarkers in Cardiovascular Patients with Acute Kidney Injury: A Case Report and Literature Review

Author:

Claure-Del Granado Rolando12ORCID,Chávez-Íñiguez Jonathan S.34ORCID

Affiliation:

1. Division of Nephrology, Hospital Obrero No 2—CNS, Cochabamba, Bolivia

2. Instituto de Investigaciones Biomédicas e Investigación Social de la Facultad de Medicina (IIBISMED), Facultad de Medicina, Universidad Mayor de San Simon, Cochabamba C.P. 3119, Bolivia

3. Division of Nephrology, Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara C.P. 44280, Mexico

4. University of Guadalajara Health Sciences Center, Guadalajara C.P. 44340, Mexico

Abstract

Biomarkers have become important tools in the diagnosis and management of cardiorenal syndrome (CRS), a complex condition characterized by dysfunction in both the cardiovascular and renal systems. Biomarkers can help identify the presence and severity of CRS, predict its progression and outcomes, and facilitate personalized treatment options. Several biomarkers, including natriuretic peptides, troponins, and inflammatory markers, have been extensively studied in CRS, and have shown promising results in improving diagnosis and prognosis. In addition, emerging biomarkers, such as kidney injury molecule-1 and neutrophil gelatinase-associated lipocalin, offer potential for early detection and intervention of CRS. However, the use of biomarkers in CRS is still in its infancy, and further research is needed to establish their utility in routine clinical practice. This review highlights the role of biomarkers in the diagnosis, prognosis, and management of CRS, and discusses their potential as valuable clinical tools for personalized medicine in the future.

Publisher

MDPI AG

Subject

Clinical Biochemistry

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