Microvascular Alteration in COVID-19 Documented by Nailfold Capillaroscopy

Author:

Mondini Lucrezia1ORCID,Confalonieri Paola1ORCID,Pozzan Riccardo1,Ruggero Luca1,Trotta Liliana1,Lerda Selene2,Hughes Michael3ORCID,Bellan Mattia456ORCID,Confalonieri Marco1ORCID,Ruaro Barbara1ORCID,Salton Francesco1ORCID,Tavano Stefano1ORCID

Affiliation:

1. Pulmonology Unit, Department of Medical Surgical and Health Sciences, University Hospital of Cattinara, University of Trieste, 34149 Trieste, Italy

2. Graduate School, University of Milan, 20149 Milano, Italy

3. Division of Musculoskeletal and Dermatological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester & Salford Royal NHS Foundation Trust, Manchester M6 8HD, UK

4. Department of Translational Medicine, Università del Piemonte Orientale (UPO), 28100 Novara, Italy

5. Center for Autoimmune and Allergic Disease (CAAD), Università del Piemonte Orientale (UPO), 28100 Novara, Italy

6. Azienda Ospedaliero–Universitaria, Maggiore della Carità, 28100 Novara, Italy

Abstract

COVID-19 is a multisystemic disease that mainly affects and causes dysregulation of the endothelium, causing systemic manifestations. A nailfold video capillaroscopy is a safe, easy, and noninvasive method to evaluate microcirculation alteration. In this review, we analyzed the literature available to date regarding the object of nailfold video capillaroscopy (NVC) use in patients with a SARS-CoV-2 infection, both in the acute phase and after discharge. The scientific evidence pointed out the main alterations in capillary circulation shown by NVC, so reviewing the findings of each article allowed us to define and analyze the future prospects and needs for possibly including NVC within the management of patients with COVID-19, both during and after the acute phase.

Publisher

MDPI AG

Subject

Clinical Biochemistry

Reference55 articles.

1. (2023, March 11). Timeline: WHO’s COVID-19 Response. Available online: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/interactive-timeline.

2. World Health Organization (2023). Therapeutics and COVID-19: Living Guideline, 13 January 2023, World Health Organization.

3. ESCMID Rapid Guidelines for Assessment and Management of Long COVID;Yelin;Clin. Microbiol. Infect.,2022

4. Cytokine Elevation in Severe and Critical COVID-19: A Rapid Systematic Review, Meta-Analysis, and Comparison with Other Inflammatory Syndromes;Leisman;Lancet Respir. Med.,2020

5. Host-Based Treatments for Severe COVID-19;Mondini;CIMB,2023

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3