Affiliation:
1. Long School of Medicine, Health Science Center, University of Texas at San Antonio, 7703 Floyd Curl Dr., San Antonio, TX 78229, USA
Abstract
Barrett’s esophagus (BE) is a change in the distal esophageal mucosal lining, whereby metaplastic columnar epithelium replaces squamous epithelium of the esophagus. This change represents a pre-malignant mucosal transformation which has a known association with the development of esophageal adenocarcinoma. Gastroesophageal reflux disease is a risk factor for BE, other risk factors include patients who are Caucasian, age > 50 years, central obesity, tobacco use, history of peptic stricture and erosive gastritis. Screening for BE remains selective based on risk factors, a screening program in the general population is not routinely recommended. Diagnosis of BE is established with a combination of endoscopic recognition, targeted biopsies, and histologic confirmation of columnar metaplasia. We aim to provide a comprehensive review of the epidemiology, pathogenesis, screening and advanced techniques of detecting and eradicating Barrett’s esophagus.
Reference94 articles.
1. Lowe, D., Kudaravalli, P., and Hsu, R. (2022, February 11). Barrett Metaplasia. [Updated 2 May 2022], StatPearls, Available online: https://www.ncbi.nlm.nih.gov/books/NBK459330/.
2. Barrett’s esophagus;Spechler;N. Engl. J. Med.,2014
3. The prevalence of Barrett’s esophagus in the US: Estimates from a simulation model confirmed by SEER data;Hayeck;Dis. Esophagu.,2010
4. Pathophysiology and treatment of Barrett’s esophagus;Oh;World J. Gastroenterol.,2010
5. Inflammation and specialized intestinal metaplasia of cardiac mucosa is a manifestation of gastroesophageal reflux disease;Oberg;Ann. Surg.,1997
Cited by
8 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献