The Correlation between Cardiac Magnetic Resonance Findings and Post-COVID-19: The Impact of Myocardial Injury on Quality of Life-Reference-Cited by-同舟云学术

The Correlation between Cardiac Magnetic Resonance Findings and Post-COVID-19: The Impact of Myocardial Injury on Quality of Life

Published:2024-09-02 Issue:17 Volume:14 Page:1937
ISSN:2075-4418
Container-title:Diagnostics
language:en
Short-container-title:Diagnostics

Author:

Popovic Maja¹,Cvetic Vladimir²³^ORCID,Popadic Viseslav⁴^ORCID,Ilic Kristina¹,Radojevic Aleksandra⁴^ORCID,Klasnja Andrea⁴,Milic Natasa³⁵⁶,Rajovic Nina³⁵,Lasica Ratko³⁷^ORCID,Gostiljac Drasko³⁸,Klasnja Slobodan⁴^ORCID,Mahmutovic Edvin⁹,Zdravkovic Marija³⁴^ORCID

Affiliation:

1. Department for Radiology, University Hospital Medical Center Bežanijska kosa, 11000 Belgrade, Serbia

2. Department for Cardiovascular Radiology, University Clinical Centre of Serbia, 11000 Belgrade, Serbia

3. Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia

4. Department for Cardiology, University Hospital Medical Center Bežanijska kosa, 11000 Belgrade, Serbia

5. Institute for Medical Statistics and Informatics, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia

6. Department of Internal Medicine, Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN 55905, USA

7. Clinic of Cardiology, Clinical Center of Serbia, 11000 Belgrade, Serbia

8. Clinic of Endocrinology, Diabetes and Metabolic Diseases, Clinical Center of Serbia, 11000 Belgrade, Serbia

9. General Hospital of Novi Pazar, 36300 Novi Pazar, Serbia

Abstract

Background: In the post-COVID-19 era, there is growing concern regarding its impact on cardiovascular health and the following effects on the overall quality of life of affected individuals. This research seeks to investigate cardiac magnetic resonance (CMR) findings following COVID-19 and their impact on the quality of life of affected individuals. Methods: An observational, cross-sectional study was conducted in consecutive patients with persistent cardiovascular symptoms after COVID-19 who were referred to CMR due to suspected myocardial injury. In addition, patients completed a questionnaire about symptoms and the quality of life during the post-COVID-19 period. Results: In this study, 85 patients were included. The study population consisted of patients with a mean age of 42.5 ± 13.4 years, predominantly women, who made up 69.4% of the study population, while men made up 30.6%. CMR findings showed non-ischemic myocardial injury in 78.8% of patients and myocardial edema in 14.1% of patients. Late pericardial enhancement was present in 40% of patients and pericardial effusion in 51.8% of patients. Pericardial effusion (p = 0.001) was more prevalent in patients who reported more pronounced symptoms in the post-COVID-19 period compared to the acute infection phase. Predictors of lower quality of life in the post-COVID-19 period were the presence of irregular heartbeat (p = 0.039), cardiovascular problems that last longer than 12 weeks (p = 0.018), and the presence of pericardial effusion (p = 0.037). Conclusion: Acute myocarditis was observed in a minority of patients after COVID-19, while non-ischemic LGE pattern and pericardial effusion were observed in the majority. Quality of life was worse during the post-COVID-19 period in patients with CMR abnormalities, primarily in patients with pericardial effusion. Also, irregular heartbeat, cardiovascular symptoms that last longer than 12 weeks, as well as pericardial effusion were independent predictors of lower quality of life during the post-COVID-19 period.

Funder

Faculty of Medicine, University of Belgrade

Publisher

MDPI AG

Link

https://www.mdpi.com/2075-4418/14/17/1937/pdf

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