Clinical and Dermoscopic Characteristics of Cutaneous Sarcomas: A Literature Review

Author:

Apalla Zoe1,Liopyris Konstantinos2,Kyrmanidou Eirini1,Fotiadou Christina1ORCID,Sgouros Dimitrios3ORCID,Patsatsi Aikaterini1ORCID,Trakatelli Myrto-Georgia1,Kalloniati Evangelia1,Lallas Aimilios4ORCID,Lazaridou Elizabeth1ORCID

Affiliation:

1. Second Dermatology Department, Aristotle University of Thessaloniki, 55535 Thessaloniki, Greece

2. First Dermatology Department, National and Kapodistrian University of Athens, 16121 Athens, Greece

3. Second Dermatology Department, National and Kapodistrian University of Athens, 16121 Athens, Greece

4. First Dermatology Department, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece

Abstract

Under the umbrella of cutaneous sarcomas (CS) we include a heterogeneous group of rare, malignant, mesenchymal neoplasia, such as dermatofibrosarcoma protuberans, atypical fibroxanthoma, cutaneous undifferentiated pleomorphic sarcoma, cutaneous angiosarcoma and leiomyosarcoma. Clinical presentation and histopathological examination are the cornerstone of CS diagnosis and classification. There are scarce data in the literature in regards to the clinical and dermatoscopic characteristics of CS and the role of dermatoscopy in their early identification. We performed a literature review, aiming to summarize current data on the clinical and dermatoscopic presentation of the most common types of cutaneous sarcomas that may facilitate early diagnosis and prompt management. Based on the available published data, CS are characterized by mostly unspecific dermatoscopic patterns. Dermatofibrosarcoma protuberans, Kaposi’s sarcoma, and in a lesser degree, cutaneous angiosarcoma, may display distinct dermatoscopic features, facilitating their early clinical recognition. In conclusion, dermatoscopy, in conjunction with the overall clinical context, may aid towards suspicion of CS.

Publisher

MDPI AG

Subject

Clinical Biochemistry

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