Long COVID in Children: A Multidisciplinary Review-Reference-Cited by-同舟云学术

Long COVID in Children: A Multidisciplinary Review

Published:2023-06-07 Issue:12 Volume:13 Page:1990
ISSN:2075-4418
Container-title:Diagnostics
language:en
Short-container-title:Diagnostics

Author:

Sansone Francesco¹,Pellegrino Giulia Michela²,Caronni Antonio³⁴^ORCID,Bonazza Federica⁵,Vegni Elena⁵⁶,Lué Alberto⁷^ORCID,Bocci Tommaso⁸⁹^ORCID,Pipolo Carlotta¹⁰,Giusti Giuliano¹¹,Di Filippo Paola¹²^ORCID,Di Pillo Sabrina¹²,Chiarelli Francesco¹²,Sferrazza Papa Giuseppe Francesco¹³^ORCID,Attanasi Marina¹²^ORCID

Affiliation:

1. Unit of Paediatrics, Rovigo Hospital, 45030 Rovigo, Italy

2. Department of Neurorehabilitation Sciences, Casa di Cura Igea, 20144 Milan, Italy

3. Department of Neurorehabilitation Sciences, IRCCS Istituto Auxologico Italiano, Ospedale San Luca, 20122 Milan, Italy

4. Department of Biomedical Sciences for Health, Università degli Studi di Milano, 20133 Milan, Italy

5. Department of Health Sciences, Clinical Psychology, University of Milan, Via di Rudinì 8, 20142 Milan, Italy

6. Unit of Clinical Psychology, San Paolo Hospital, ASST Santi Paolo e Carlo, Via di Rudinì 8, 20142 Milan, Italy

7. Service of Digestive Diseases, University Clinic Hospital Lozano Blesa, IIS Aragón, 50009 Zaragoza, Spain

8. Department of Health Sciences, University of Milan, 20146 Milan, Italy

9. Clinical Neurology Unit, Department of Health Sciences, “Azienda Socio-Sanitaria Territoriale Santi Paolo e Carlo”, University of Milan, 20146 Milan, Italy

10. Department of Health Sciences, Otorhinolaryngology Department, ASST Santi Paolo e Carlo, University of Milan, 20142 Milan, Italy

11. Paediatric Cardiology Unit, Niguarda Hospital, 20162 Milan, Italy

12. Paediatric Allergy and Pulmonology Unit, Department of Paediatrics, University of Chieti-Pescara, 66100 Chieti, Italy

13. School of Medicine, University of Enna “Kore”, 94100 Enna, Italy

Abstract

Long COVID syndrome has emerged as a long-lasting consequence of acute SARS-CoV-2 infection in adults. In addition, children may be affected by Long COVID, with potential clinical issues in different fields, including problems in school performance and daily activities. Yet, the pathophysiologic bases of Long COVID in children are largely unknown, and it is difficult to predict who will develop the syndrome. In this multidisciplinary clinical review, we summarise the latest scientific data regarding Long COVID and its impact on children. Special attention is given to diagnostic tests, in order to help the physicians to find potential disease markers and quantify impairment. Specifically, we assess the respiratory, upper airways, cardiac, neurologic and motor and psychological aspects. Finally, we also propose a multidisciplinary clinical approach.

Funder

Università degli Studi di Milano

Publisher

MDPI AG

Subject

Clinical Biochemistry

Link

https://www.mdpi.com/2075-4418/13/12/1990/pdf

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