One-Year Follow-Up Lung Ultrasound of Post-COVID Syndrome—A Pilot Study

Author:

Altersberger Martin1,Grafeneder Anna1,Cho Yerin1,Winkler Roland2,Zwick Ralf3,Mathis Gebhard4,Genger Martin1

Affiliation:

1. Department of Cardiology, Nephrology and Intensive Care Medicine, State Hospital Steyr, 4400 Steyr, Austria

2. Rehabilitation Center Hochegg for Cardiovascular and Respiratory Diseases, 2840 Grimmenstein, Austria

3. Therme Wien Med, 1100 Vienna, Austria

4. Praxis of Internal Medicine, 6830 Rankweil, Austria

Abstract

(1) Background: Millions of people worldwide were infected with COVID-19. After the acute phase of the disease, many suffer from prolonged symptoms, the post-COVID syndrome, especially the phenotype with lung residuals. Many open questions regarding lung ultrasound (LUS) have to be answered. One essential question is the means for optimal following-up of patients with post-COVID-19 residuals with LUS; (2) Methods: A retrospective data analysis of patients after acute COVID-19 infection diagnosed with post-COVID syndrome in the state hospital of Steyr and the rehabilitation center of Hochegg was performed. LUS examinations following a 12-zone scanning protocol were performed, and the LUS score quantified comet tail artifacts. A total of 16 patients were evaluated twice with LUS from May 2020 until June 2021. (3) Results: All patients’ reverberation artifacts were reduced over time. The initial LUS score of 17.75 (SD 4.84) points was decreased over the duration of the second rehabilitation to 8,2 (SD 5.94). The difference in the Wilcoxon test was significant (p < 0.001); (4) Conclusions: Lung ultrasound was a valuable tool in the follow-up of post-COVID-syndrome with lung residuals in the first wave of COVID-19. A reduction in reverberation artifacts was demonstrated. Further studies about the clinical significance have to follow.

Publisher

MDPI AG

Subject

Clinical Biochemistry

Reference44 articles.

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2. Carod-Artal, F.J. (2021). Post-COVID-19 syndrome: Epidemiology, diagnostic criteria and pathogenic mechanisms involved. Rev. Neurol.

3. Lung Ultrasound in COVID-19 and Post-COVID-19 Patients, an Evidence-Based Approach;Santacroce;J. Ultrasound Med.,2021

4. WFUMB position paper on reverberation artefacts in lung ultrasound: B-lines or comet-tails?;Mathis;Med. Ultrason,2020

5. Demi, L., Wolfram, F., Klersy, C., De Silvestri, A., Ferretti, V.V., Muller, M., Miller, D., Feletti, F., Wełnicki, M., and Buda, N. (2022). New International Guidelines and Consensus on the Use of Lung Ultrasound. J. Ultrasound Med.

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