Overlap of Suspicious and Non-Suspicious Features in the Ultrasound Evaluations of Leiomyosarcoma: A Single-Center Experience

Author:

Arezzo Francesca12,Cormio Gennaro13ORCID,Putino Carmela2,Di Lillo Nicola2,Silvestris Erica1ORCID,Kardhashi Anila1,Cazzolla Ambrogio1,Lombardi Claudio2,Mongelli Michele2ORCID,Cazzato Gerardo4ORCID,Loizzi Vera3ORCID

Affiliation:

1. Gynecologic Oncology Unit, IRCCS Istituto Tumori “Giovanni Paolo II”, 70124 Bari, Italy

2. Department of Biomedical Sciences and Human Oncology, University of Bari “Aldo Moro”, 70124 Bari, Italy

3. Interdisciplinar Department of Medicine, University of Bari “Aldo Moro”, 70124 Bari, Italy

4. Section of Molecular Pathology, Department of Emergency and Organ Transplantation, University of Bari “Aldo Moro”, 70124 Bari, Italy

Abstract

Leiomyosarcoma (LMS) is a rare type of mesenchymal tumor. Suspecting LMS before surgery is crucial for proper patient management. Ultrasound is the primary method for assessing myometrial lesions. The overlapping of clinical, laboratory, as well as ultrasound features between fibroids and LMS makes differential diagnosis difficult. We report our single-center experience in ultrasound imaging assessment of LMS patients, highlighting that misleading findings such as shadowing and absent or minimal vascularization may also occur in LMS. To avoid mistakes, a comprehensive evaluation of potentially overlapping ultrasound features is necessary in preoperative ultrasound evaluations of all myometrial tumors.

Funder

Italian Ministry of Health, Ricerca Corrente 202 deliberation

Publisher

MDPI AG

Subject

Clinical Biochemistry

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