Occult Breast Cancer Presenting as Sternum Pain-Reference-Cited by-同舟云学术

Occult Breast Cancer Presenting as Sternum Pain

Published:2024-04-04 Issue:7 Volume:14 Page:765
ISSN:2075-4418
Container-title:Diagnostics
language:en
Short-container-title:Diagnostics

Author:

Wu Dang¹²,Guo Siyu¹²,Zhang Bicheng¹²,Huang Fengbo²³,Qian Wei⁴,Qiu Fuming²⁵,Wei Qichun¹²^ORCID,Zhang Ting¹²^ORCID

Affiliation:

1. Department of Radiation Oncology, Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou 310009, China

2. Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, National Ministry of Education), Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou 310009, China

3. Department of Pathology, Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou 310009, China

4. Department of Radiology, Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou 310009, China

5. Department of Oncology, Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou 310009, China

Abstract

Bone metastasis has been reported in up to 70% of patients with advanced breast cancer. A total of 55.76% of skeletal metastases in women were derived from breast cancer. However, patients with bone metastasis from an occult primary breast cancer are a rare subset of patients. Here, we present the case of a 38-year-old woman who had sternum pain for 4 months. A whole-body PET-CT scan revealed that the FDG uptake of both the sternum and internal mammary node was significantly increased. The final diagnosis of occult breast cancer was established by immunohistochemical (IHC) staining, which is of great significance for identifying the origin of a metastatic tumor despite no visualized lesions of mammary glands.

Funder

National Natural Science Foundation of China

Immunoradiotherapy Research Fund of Chinese Society of Radiation Oncology

Publisher

MDPI AG

Link

https://www.mdpi.com/2075-4418/14/7/765/pdf

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