Small Bowel Perforation Due to Renal Carcinoma Metastasis: A Comprehensive Case Study and Literature Review

Author:

Todorovic Đorđe1,Stojanovic Bojan2ORCID,Filip Milutinovic1,Đorđevic Đorđe1,Stankovic Milos2,Jovanovic Ivan3ORCID,Spasic Marko2ORCID,Milosevic Bojan2,Cvetkovic Aleksandar2,Radovanovic Dragce2,Jovanovic Marina4,Stojanovic Bojana S.5,Pantic Damnjan12,Cvetkovic Danijela6ORCID,Jovanovic Dalibor7,Markovic Vladan8ORCID,Stojanovic Milica Dimitrijevic7

Affiliation:

1. Department of Urology, University Clinical Center Kragujevac, 34000 Kragujevac, Serbia

2. Department of Surgery, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia

3. Center for Molecular Medicine and Stem Cell Research, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia

4. Department of Internal Medicine, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia

5. Department of Pathophysiology, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia

6. Department of Genetics, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia

7. Department of Pathology, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia

8. Department of Radiology, Faculty of Medical Sciences, University of Kragujevac, 34000 Kragujevac, Serbia

Abstract

This case report presents a unique instance of small bowel perforation caused by solitary metastasis from renal cell carcinoma (RCC), a rare and complex clinical scenario. The patient, a 59-year-old male with a history of RCC treated with nephrectomy four years prior, presented with acute abdomen symptoms. Emergency diagnostic procedures identified a significant lesion in the small intestine. Surgical intervention revealed a perforated jejunal segment due to metastatic RCC. Postoperatively, the patient developed complications, including pneumonia and multi-organ failure, leading to death 10 days after surgery. Histopathological analysis confirmed the metastatic nature of the lesion. This case underscores the unpredictable nature of RCC metastasis and highlights the need for vigilance in post-nephrectomy patients. The rarity of small bowel involvement by RCC metastasis, particularly presenting as perforation, makes this case a significant contribution to medical literature, emphasizing the challenges in the diagnosis and management of such atypical presentations.

Funder

Serbian Ministry of Science, Technological Development, and Innovation

Faculty of Medical Sciences at the University of Kragujevac, Serbia

Publisher

MDPI AG

Reference50 articles.

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