Dual-Tracer Positron Emission Tomography/Computed Tomography with [18F]FDG and [18F]fluorocholine in a Patient with Metastatic Parathyroid Carcinoma

Author:

Iacovitti Cesare Michele1,Cuzzocrea Marco1ORCID,Gianola Lauro2,Paone Gaetano13,Treglia Giorgio134ORCID

Affiliation:

1. Division of Nuclear Medicine, Imaging Institute of Southern Switzerland, Ente Ospedaliero Cantonale, 6500 Bellinzona, Switzerland

2. Service of Endocrinology, Department of Medicine, Ente Ospedaliero Cantonale, 6850 Mendrisio, Switzerland

3. Faculty of Biomedical Sciences, Università della Svizzera italiana, 6900 Lugano, Switzerland

4. Faculty of Biology and Medicine, University of Lausanne, 1015 Lausanne, Switzerland

Abstract

Here, we describe the case of a 43-year-old male patient with a metastatic parathyroid carcinoma who underwent dual-tracer whole-body positron emission tomography/computed tomography (PET/CT) with [18F]fluorocholine and fluorodeoxyglucose ([18F]FDG) for staging. [18F]FDG PET/CT detected multiple cervical and mediastinal lymph nodal lesions with increased tracer uptake, whereas [18F]fluorocholine PET/CT detected increased tracer uptake on cervical and mediastinal lymph nodal lesions and bone and lung lesions with a better evaluation of metastatic spread. Due to these imaging findings, the patient underwent systemic treatment with chemotherapy. This case demonstrates the added value of dual-tracer PET/CT in this rare metastatic tumor.

Publisher

MDPI AG

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