Diagnosis of Migrainous Infarction: A Case Report and Analysis of Previously Published Cases

Author:

Lebedeva Elena R.12ORCID,Gurary Natalia M.3,Olesen Jes4

Affiliation:

1. Department of Neurology, The Ural State Medical University, 620028 Yekaterinburg, Russia

2. International Headache Centre “Europe-Asia”, 620144 Yekaterinburg, Russia

3. Medical Union “New Hospital”, 620028 Yekaterinburg, Russia

4. Danish Headache Centre, Department of Neurology, Rigshospitalet-Glostrup, University of Copenhagen, 1172 Copenhagen, Denmark

Abstract

Migrainous infarction (MI) is a rare disorder. The precise diagnostic criteria for this diagnosis have been available in the International Classification of Headache Disorders (ICHD) since 1988, but many cases do not fulfil these criteria. This paper describes a good example of MI and analyzes previously published case reports. We report a very special case of MI in an 18-year-old woman who had a recurrent episode of migraine with a similar aura with numbness of the right arm and speech disturbances which had an unusually long duration (>120 min). On admission to the headache centre “Europe-Asia”, she complained of slowness of speech and problems with choice of words. An MRI showed acute lacunar infarcts in the left parietal subcortical area. Ischemic infarcts were localized in a relevant area on the left side and the aura symptoms were right-sided. The patient, therefore, fulfilled the ICHD-3 diagnostic criteria for “Migrainous infarction”. An analysis of 35 previously published articles with case reports about MI showed that 22 did not meet the diagnostic criteria of the ICHD for migrainous infarction. Using all this, we developed diagnostic recommendations for migrainous infarction which can help to improve the quality of diagnosis when used together with the diagnostic criteria of the ICHD for migrainous infarction.

Publisher

MDPI AG

Subject

Clinical Biochemistry

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2. (1988). The International Classification of Headache Disorders, SAGE Publications. [1st ed.]. (ICHD-1).

3. (2018). The International Classification of Headache Disorders, SAGE Publications. [3rd ed.]. (ICHD-3).

4. Microembolism and Other Links Between Migraine and Stroke: Clinical and Pathophysiologic Update;Sacco;Neurology,2023

5. Migraine and Ischemic Stroke: Deciphering the Bidirectional Pathway;Raut;ACS Chem. Neurosci.,2020

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