Spinal Schwannomatosis Mimicking Metastatic Extramedullary Spinal Tumor

Author:

Nurdillah Idris1ORCID,Rizuana Iqbal Hussain1ORCID,Syazarina Sharis Osman1

Affiliation:

1. Department of Radiology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Center, Jalan Yaakob Latif, Kuala Lumpur 56000, Malaysia

Abstract

Intradural extramedullary (IDEM) tumors are the most commonly observed intraspinal tumors, comprising over 60% of tumors found within the spinal canal, and the vast majority of these lesions are benign lesions. IDEM metastases are rare, but if they occur, they commonly manifest as leptomeningeal disease, secondary to drop lesions from intracranial metastases from adenocarcinomas of the lung, prostate cancer, breast cancer, melanoma, or rarely, as a result of lymphomas. The purely non-neurogenic origin of IDEM metastases is rare. Herein, we describe a patient with a previous history of treated colon cancer who presented with a progressive neurological deficit and whose imaging revealed multiple intradural, extramedullary and osseous lesions at the cervical and thoracolumbar spines. With the previous known primary and multiplicity of the lesions, an initial diagnosis of spinal metastasis was made, But it was proven to be schwannoma on histology. We emphasize the diagnostic dilemma in this case and the importance of detecting subtle imaging findings, which may be helpful to differentiate between metastatic disease and a second primary tumor.

Funder

the Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Center

Publisher

MDPI AG

Subject

Clinical Biochemistry

Reference20 articles.

1. Single Cell Transcriptome in Colorectal Cancer-Current Updates on Its Application in Metastasis, Chemoresistance and the Roles of Circulating Tumor Cells;Tieng;Front. Pharmacol.,2020

2. Osteofibrous Dysplasia-Like Adamantinoma Mimicking Bone Metastasis in A Patient with Rectosigmoid Cancer;Thanuja;Malays. J. Med. Health Sci.,2021

3. Adult intradural primary spinal cord tumors;Aghayev;J. Natl. Compr. Canc. Netw.,2011

4. Surgery of spinal nerve sheath tumors with special reference to neurofibromatosis;Klekamp;Neurosurgery,1998

5. Intradural spinal tumors: Current classification and MRI features;Thurnher;Neuroradiology,2008

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3