Accurate and Reliable Classification of Unstructured Reports on Their Diagnostic Goal Using BERT Models

Author:

Rietberg Max Tigo1ORCID,Nguyen Van Bach2ORCID,Geerdink Jeroen3ORCID,Vijlbrief Onno3ORCID,Seifert Christin2ORCID

Affiliation:

1. Faculty of EEMCS, University of Twente, 7500 AE Enschede, The Netherlands

2. Institute for Artificial Intelligence in Medicine, University of Duisburg-Essen, 45131 Essen, Germany

3. Hospital Group Twente (ZGT), 7555 DL Hengelo, The Netherlands

Abstract

Understanding the diagnostic goal of medical reports is valuable information for understanding patient flows. This work focuses on extracting the reason for taking an MRI scan of Multiple Sclerosis (MS) patients using the attached free-form reports: Diagnosis, Progression or Monitoring. We investigate the performance of domain-dependent and general state-of-the-art language models and their alignment with domain expertise. To this end, eXplainable Artificial Intelligence (XAI) techniques are used to acquire insight into the inner workings of the model, which are verified on their trustworthiness. The verified XAI explanations are then compared with explanations from a domain expert, to indirectly determine the reliability of the model. BERTje, a Dutch Bidirectional Encoder Representations from Transformers (BERT) model, outperforms RobBERT and MedRoBERTa.nl in both accuracy and reliability. The latter model (MedRoBERTa.nl) is a domain-specific model, while BERTje is a generic model, showing that domain-specific models are not always superior. Our validation of BERTje in a small prospective study shows promising results for the potential uptake of the model in a practical setting.

Funder

Open Access Publication Fund of the University of Duisburg-Essen

Publisher

MDPI AG

Subject

Clinical Biochemistry

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