First Results of a New Deep Learning Reconstruction Algorithm on Image Quality and Liver Metastasis Conspicuity for Abdominal Low-Dose CT

Author:

Greffier Joël1ORCID,Durand Quentin1,Serrand Chris2ORCID,Sales Renaud1ORCID,de Oliveira Fabien1,Beregi Jean-Paul1,Dabli Djamel1,Frandon Julien1ORCID

Affiliation:

1. IMAGINE UR UM 103, Department of Medical Imaging, Nimes University Hospital, Montpellier University, 30029 Nimes, France

2. Department of Biostatistics, Clinical Epidemiology, Public Health, and Innovation in Methodology (BESPIM), CHU Nimes, 30029 Nimes, France

Abstract

The study’s aim was to assess the impact of a deep learning image reconstruction algorithm (Precise Image; DLR) on image quality and liver metastasis conspicuity compared with an iterative reconstruction algorithm (IR). This retrospective study included all consecutive patients with at least one liver metastasis having been diagnosed between December 2021 and February 2022. Images were reconstructed using level 4 of the IR algorithm (i4) and the Standard/Smooth/Smoother levels of the DLR algorithm. Mean attenuation and standard deviation were measured by placing the ROIs in the fat, muscle, healthy liver, and liver tumor. Two radiologists assessed the image noise and image smoothing, overall image quality, and lesion conspicuity using Likert scales. The study included 30 patients (mean age 70.4 ± 9.8 years, 17 men). The mean CTDIvol was 6.3 ± 2.1 mGy, and the mean dose-length product 314.7 ± 105.7 mGy.cm. Compared with i4, the HU values were similar in the DLR algorithm at all levels for all tissues studied. For each tissue, the image noise significantly decreased with DLR compared with i4 (p < 0.01) and significantly decreased from Standard to Smooth (−26 ± 10%; p < 0.01) and from Smooth to Smoother (−37 ± 8%; p < 0.01). The subjective image assessment confirmed that the image noise significantly decreased between i4 and DLR (p < 0.01) and from the Standard to Smoother levels (p < 0.01), but the opposite occurred for the image smoothing. The highest scores for overall image quality and conspicuity were found for the Smooth and Smoother levels.

Publisher

MDPI AG

Subject

Clinical Biochemistry

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