Artificial Intelligence-Aided Diagnosis Solution by Enhancing the Edge Features of Medical Images

Author:

Lv Baolong1,Liu Feng23,Li Yulin1ORCID,Nie Jianhua4,Gou Fangfang5,Wu Jia56ORCID

Affiliation:

1. School of Modern Service Management, Shandong Youth University of Political Science, Jinan 250102, China

2. School of Information Engineering, Shandong Youth University of Political Science, Jinan 250102, China

3. New Technology Research and Development Center of Intelligent Information Controlling in Universities of Shandong, Jinan 250103, China

4. Shandong Provincial People’s Government Administration Guarantee Center, Jinan 250011, China

5. School of Computer Science and Engineering, Central South University, Changsha 410017, China

6. Research Center for Artificial Intelligence, Monash University, Melbourne, VIC 3800, Australia

Abstract

Bone malignant tumors are metastatic and aggressive. The manual screening of medical images is time-consuming and laborious, and computer technology is now being introduced to aid in diagnosis. Due to a large amount of noise and blurred lesion edges in osteosarcoma MRI images, high-precision segmentation methods require large computational resources and are difficult to use in developing countries with limited conditions. Therefore, this study proposes an artificial intelligence-aided diagnosis scheme by enhancing image edge features. First, a threshold screening filter (TSF) was used to pre-screen the MRI images to filter redundant data. Then, a fast NLM algorithm was introduced for denoising. Finally, a segmentation method with edge enhancement (TBNet) was designed to segment the pre-processed images by fusing Transformer based on the UNet network. TBNet is based on skip-free connected U-Net and includes a channel-edge cross-fusion transformer and a segmentation method with a combined loss function. This solution optimizes diagnostic efficiency and solves the segmentation problem of blurred edges, providing more help and reference for doctors to diagnose osteosarcoma. The results based on more than 4000 osteosarcoma MRI images show that our proposed method has a good segmentation effect and performance, with Dice Similarity Coefficient (DSC) reaching 0.949, and show that other evaluation indexes such as Intersection of Union (IOU) and recall are better than other methods.

Funder

the Shandong Humanities and Social Sciences Project

Publisher

MDPI AG

Subject

Clinical Biochemistry

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