A Model for Diagnosing Autism Patients Using Spatial and Statistical Measures Using rs-fMRI and sMRI by Adopting Graphical Neural Networks

Abstract

This article proposes a model to diagnose autism patients using graphical neural networks. A graphical neural network relates the subjects (nodes) using the features (edges). In our model, radiomic features obtained from sMRI are used as edges, and spatial-temporal data obtained through rs-fMRI are used as nodes. The similarity between first-order and texture features from the sMRI data of subjects are derived using radiomics to construct the edges of a graph. The features from brain summaries are assembled and learned using 3DCNN to represent the features of each node of the graph. Using the structural similarities of the brain rather than phenotypic data or graph kernel functions provides better accuracy. The proposed model was applied to a standard dataset, ABIDE, and it was shown that the classification results improved with the use of both spatial (sMRI) and statistical measures (brain summaries of rs-fMRI) instead of using only medical images.