Rise of the BQ.1.1.37 SARS-CoV-2 Sublineage, Italy-Reference-Cited by-同舟云学术

Rise of the BQ.1.1.37 SARS-CoV-2 Sublineage, Italy

Published:2023-03-06 Issue:5 Volume:13 Page:1000
ISSN:2075-4418
Container-title:Diagnostics
language:en
Short-container-title:Diagnostics

Author:

Focosi Daniele¹^ORCID,Spezia Pietro Giorgio²^ORCID,Capria Anna-Lisa²,Gueli Federico³,McConnell Scott⁴^ORCID,Novazzi Federica⁵,Pistello Mauro²⁵⁶^ORCID

Affiliation:

1. North-Western Tuscany Blood Bank, Pisa University Hospital, 56124 Pisa, Italy

2. Division of Virology, Pisa University Hospital, 56124 Pisa, Italy

3. Independent Researcher, 2210 Como, Italy

4. Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA

5. Laboratory of Microbiology, ASST Sette Laghi, 21100 Varese, Italy

6. Retrovirus Center and Virology Section, Department of Translational Research, University of Pisa, 56100 Pisa, Italy

Abstract

BQ.1.1 has dominated the Europe and Americas COVID-19 wave across the 2022–2023 winter, and further viral evolution is expected to escape the consolidating immune responses. We report here the emergence of the BQ.1.1.37 variant in Italy, peaking in January 2022 before suffering competition by XBB.1.*. We attempted to correlate the potential fitness of BQ.1.1.37 with a unique two-amino acid insertion within the Spike protein.

Funder

bando Ricerca Salute 2018

Publisher

MDPI AG

Subject

Clinical Biochemistry

Link

https://www.mdpi.com/2075-4418/13/5/1000/pdf

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