A Web-Based Platform for the Automatic Stratification of ARDS Severity

Author:

Yahyatabar Mohammad1ORCID,Jouvet Philippe2ORCID,Fily Donatien2,Rambaud Jérome2ORCID,Levy Michaël2ORCID,Khemani Robinder G.3,Cheriet Farida1ORCID

Affiliation:

1. Department of Computer and Software Engineering, Polytechnique Montréal, Montréal, QC H3T 1J4, Canada

2. Department of Pediatrics, Faculty of Medicine, University of Montréal, Montréal, QC H3C 3J7, Canada

3. Department of Anesthesiology and Critical Care Medicine, Children’s Hospital of Los Angeles, Los Angeles, CA 90027, USA

Abstract

Acute respiratory distress syndrome (ARDS), including severe pulmonary COVID infection, is associated with a high mortality rate. It is crucial to detect ARDS early, as a late diagnosis may lead to serious complications in treatment. One of the challenges in ARDS diagnosis is chest X-ray (CXR) interpretation. ARDS causes diffuse infiltrates through the lungs that must be identified using chest radiography. In this paper, we present a web-based platform leveraging artificial intelligence (AI) to automatically assess pediatric ARDS (PARDS) using CXR images. Our system computes a severity score to identify and grade ARDS in CXR images. Moreover, the platform provides an image highlighting the lung fields, which can be utilized for prospective AI-based systems. A deep learning (DL) approach is employed to analyze the input data. A novel DL model, named Dense-Ynet, is trained using a CXR dataset in which clinical specialists previously labelled the two halves (upper and lower) of each lung. The assessment results show that our platform achieves a recall rate of 95.25% and a precision of 88.02%. The web platform, named PARDS-CxR, assigns severity scores to input CXR images that are compatible with current definitions of ARDS and PARDS. Once it has undergone external validation, PARDS-CxR will serve as an essential component in a clinical AI framework for diagnosing ARDS.

Funder

IVADO

Fonds de Recherche en Santé du Québec

FRQS

Publisher

MDPI AG

Subject

Clinical Biochemistry

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