Affiliation:
1. Departamento de Química (DEQ), Universidade Estadual do Centro-Oeste (UNICENTRO), Guarapuava 85040-167, PR, Brazil
2. Instituto de Química (INQUI), Universidade Federal do Mato Grosso do Sul (UFMS), Campo Grande 79074-460, MS, Brazil
3. Instituto de Química (IQ), Universidade Federal de Goiás (UFG), Goiânia 74690-900, GO, Brazil
Abstract
The 1,2,3-triazoles are an important class of organic compounds that are found in a variety of biologically active compounds. The most usual and efficient methodology to synthetize these compounds is the Copper-catalyzed Azide–Alkyne Cycloaddition (CuAAC), preferably by use of click chemistry principles. Therefore, the development of simple, robust, easily accessible and efficient materials as catalysts for this kind of reaction is highly desirable. In this sense, layered hydroxide salts (LHS) emerge as an interesting alternative for the click reaction. Thus, we describe herein the preparation and characterization of copper (II) layered hydroxide salts and their application as catalysts for the CuAAC reaction under solvent-free conditions. This synthetic methodology of CuAAC reaction is attractive as it follows several concepts of green chemistry, such as being easy to perform, allowing purification without chromatographic column, the process forming no sub-products, affording the desired 1,2,3-traizoles in the specific 1,4-disubstituted position in high yield, and having a short reaction time. Moreover, the photocatalysis for the degradation of methyl orange was also highly efficient using the same catalyst.
Funder
Coordenação de Aperfeicoamento de Pessoal de Nível Superior
National Council for Scientific and Technological Development
Subject
Physical and Theoretical Chemistry,Catalysis,General Environmental Science
Cited by
3 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献