Breast Reconstruction after Breast Implant-Associated Anaplastic Large Cell Lymphoma Treatment: A Case Report and Literature Review

Author:

Lee Won-Seob1ORCID,Kim Tae-Gon1ORCID,Lee Jun-Ho1ORCID,Kim Il-Kug1ORCID

Affiliation:

1. Department of Plastic and Reconstructive Surgery, Yeungnam University College of Medicine, Daegu 42415, Republic of Korea

Abstract

Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a T-cell non-Hodgkin’s lymphoma that occurs in patients with at least one prior textured breast implant. BIA-ALCL has a relatively good prognosis when treated promptly. However, data on the methods and timing of the reconstruction process are lacking. Herein, we report the first case of BIA-ALCL in Republic of Korea in a patient who underwent breast reconstruction using implants and an acellular dermal matrix (ADM). A 47-year-old female patient was diagnosed with BIA-ALCL stage IIA (T4N0M0) and underwent bilateral breast augmentation using textured breast implants. She then underwent removal of both breast implants, total bilateral capsulectomy, adjuvant chemotherapy, and radiotherapy. There was no evidence of recurrence at 28 months postoperatively; therefore, the patient wished to undergo breast reconstruction surgery. A smooth surface implant was used to consider the patient’s desired breast volume and body mass index. The right breast was reconstructed with a smooth surface implant and an ADM in the prepectoral plane. Breast augmentation was performed on the left breast using a smooth surface implant. The patient was satisfied with the results and recovered fully with no complications.

Funder

2020 Yeungnam University Research Grant

Publisher

MDPI AG

Subject

General Medicine

Reference24 articles.

1. Axillary Lymphadenopathy: An Outstanding Presentation for Breast Implant-Associated ALK-Negative Anaplastic Large Cell Lymphoma;Tardio;Int. J. Surg. Pathol.,2015

2. American Society of Plastic Surgeons (ASPS) (2022, September 02). BIA-ALCL Resources: Publications and Press Releases. Arlington Heights, IL: ASPS. Available online: https://www.plasticsurgery.org/for-medical-professionals/health-policy/bia-alcl-physician-resources/publications-and-press-releases.

3. Breast implant-associated anaplastic large cell lymphoma in an Asian patient: The first case report from Thailand;Thienpaitoon;Arch. Plast. Surg.,2020

4. Breast implant-associated anaplastic large-cell lymphoma: First case detected in a Japanese breast cancer patient;Ohishi;Breast Cancer,2020

5. Analysis of the Molecular Signature of Breast Implant-Associated Anaplastic Large Cell Lymphoma in an Asian Patient;Kim;Aesthet. Surg. J.,2021

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