Application of Calcium Carbonate as a Controlled Release Carrier for Therapeutic Drugs

Author:

Li Siying1ORCID,Lian Bin2ORCID

Affiliation:

1. College of Life Sciences, Nanjing Normal University, Nanjing 210023, China

2. College of Marine Science and Engineering, Nanjing Normal University, Nanjing 210023, China

Abstract

A drug carrier usually refers to a tool that can carry the effective ingredients of drugs into the human body. The drug-controlled release system prepared by a new drug carrier can allow the gradual release of the drug in the human body at a stable rate, thus decreasing the frequency of administration and reducing the toxicity and side effects thereof; however, existing drug carriers generally have problems such as low drug loading, poor biocompatibility, stability, and specificity, each of which could be improved. Calcium carbonate can be used as a sustained-release carrier of active substances, with good biocompatibility, biodegradability, low cost, easy preparation, and broad application prospects. This paper reviews the synthesis and structural characteristics of calcium carbonate carrier materials and the related research progress of calcium carbonate as a controlled release carrier for therapeutic drugs, providing a reference for promoting the research and application of calcium carbonate as a drug carrier.

Funder

National Natural Science Foundation of China

Interdisciplinary Project of Nanjing Normal University

Publisher

MDPI AG

Subject

Geology,Geotechnical Engineering and Engineering Geology

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