Exploring the Versatility of Microemulsions in Cutaneous Drug Delivery: Opportunities and Challenges

Author:

Ait-Touchente Zouhair1,Zine Nadia1,Jaffrezic-Renault Nicole1ORCID,Errachid Abdelhamid1,Lebaz Noureddine2ORCID,Fessi Hatem2,Elaissari Abdelhamid1ORCID

Affiliation:

1. Univ Lyon, Université Claude Bernard Lyon-1, CNRS, ISA-UMR 5280, 69100 Villeurbanne, France

2. Univ Lyon, Université Claude Bernard Lyon-1, CNRS, LAGEPP UMR 5007, 69100 Villeurbanne, France

Abstract

Microemulsions are novel drug delivery systems that have garnered significant attention in the pharmaceutical research field. These systems possess several desirable characteristics, such as transparency and thermodynamic stability, which make them suitable for delivering both hydrophilic and hydrophobic drugs. In this comprehensive review, we aim to explore different aspects related to the formulation, characterization, and applications of microemulsions, with a particular emphasis on their potential for cutaneous drug delivery. Microemulsions have shown great promise in overcoming bioavailability concerns and enabling sustained drug delivery. Thus, it is crucial to have a thorough understanding of their formulation and characterization in order to optimize their effectiveness and safety. This review will delve into the different types of microemulsions, their composition, and the factors that affect their stability. Furthermore, the potential of microemulsions as drug delivery systems for skin applications will be discussed. Overall, this review will provide valuable insights into the advantages of microemulsions as drug delivery systems and their potential for improving cutaneous drug delivery.

Publisher

MDPI AG

Subject

General Materials Science,General Chemical Engineering

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