Internet-Purchased Sodium Azide Used in a Fatal Suicide Attempt: A Case Report and Review of the Literature

Author:

van der Heijden Lisa T.12ORCID,van den Hondel Karen E.3,Olyslager Erik J. H.4,de Jong Lutea A. A.4ORCID,Reijnders Udo J. L.3,Franssen Eric J. F.5

Affiliation:

1. Department of Pharmacy & Pharmacology, Antoni van Leeuwenhoek/The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands

2. Division of Pharmacology, Antoni van Leeuwenhoek/The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands

3. Department of Forensic Medicine, GGD Amsterdam, 1066 CX Amsterdam, The Netherlands

4. Department of Clinical Pharmacy, Expert Center Gelre-iLab, Gelre Hospitals, 1066 CX Apeldoorn/Zutphen, The Netherlands

5. Department of Clinical Pharmacy, OLVG Hospital, 1066 CX Amsterdam, The Netherlands

Abstract

There has been a significant increase in sodium azide intoxications since the 1980s. Intoxications caused by sodium azide are becoming increasingly prevalent in the Netherlands as a result of its promotion for the purpose of self-euthanasia. The mechanism of toxicity is not completely understood but is dose-dependent. The presented case describes a suicide by sodium azide of a young woman (26 years old) with a history of depression and suicide attempts. The decedent was found in the presence of prescription medicine, including temazepam, domperidone in combination with omeprazole, and the chemical preservative sodium azide. Quantitative toxicology screening of whole blood revealed the presence of 70 µg/L temazepam (toxic range > 1000 µg/L) and 28 mg/L sodium azide (fatal range: 2.6–262 mg/L). Whole blood qualitative analysis revealed the presence of temazepam, temazepam-glucuronide, olanzapine, n-desmethylolanzapine, and acetaminophen. In circles promoting sodium azide, it is recommended to use sodium azide in combination with medications targeting sodium azide’s negative effects, such as analgesics, antiemetics, and anti-anxiety drugs. The medicines recovered at the body’s location, as well as the results of the toxicology screens, were consistent with the recommendations of self-euthanasia using sodium azide.

Publisher

MDPI AG

Subject

Chemical Health and Safety,Health, Toxicology and Mutagenesis,Toxicology

Reference28 articles.

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