1. Laboratory of Pharmacokinetics and Toxicology, La Timone University Hospital, 264 Rue Saint Pierre, CEDEX 5, 13385 Marseille, France
2. Intensive Care Unit, Laveran Military Teaching Hospital, 34 Boulevard Laveran, 13384 Marseille, France
3. Department of Clinical Pharmacology and Pharmacovigilance, La Timone University Hospital, 264 Rue Saint Pierre, CEDEX 5, 13385 Marseille, France
4. Institut de Neurosciences des Systèmes, Aix Marseille University, INSERM UMR 1106, 13385 Marseille, France
5. Economic and Social Sciences of Health and Medical Information Processing, Aix Marseille University, INSERM UMR 1252, IRD, SESSTIM, 13385 Marseille, France