Abstract
Ketosis is a metabolic disease of pregnant and lactating ewes linked to a negative energy balance which can cause different economic losses. The aims of this study were to understand the metabolic status of the early-lactating ewes and to identify biomarkers for early diagnosis of subclinical ketosis. Forty-six Sarda ewes were selected in the immediate post-partum for the collection of the biological samples. A blood sample from the jugular vein was used to determine β-Hydroxybutyrate (BHB) concentrations. Animals were divided into two groups: BHB 0 or healthy group (n = 28) with BHB concentration < 0.86 mmol/L; and BHB 1 or subclinical ketosis (n = 18) with a BHB concentration ≥ 0.86 mmol/L. Ten mL of pool milk were collected at the morning milking for the analyses. The concentration of 34 milk fatty acids was evaluated using gas chromatography. Two biochemical parameters and 11 milk fatty acids of the total lipid fraction presented a p-value ≤ 0.05. The study revealed different relationships with tricarboxylic acid cycle, blood flows, immune and nervous systems, cell functions, inflammatory response, and oxidative stress status. Eight parameters were significant for the receiver operating characteristic (ROC) analysis with an area under the curve greater than 0.70.
Subject
General Veterinary,Animal Science and Zoology
Reference39 articles.
1. Subclinical and Clinical Ketosis in Sheep-Relationships Between Body Condition Scores and Blood Β-Hydroxybutyrate and Non-Esterified Fatty Acids Concentrations;Marutsova;Tradit. Mod. Vet. Med.,2018
2. Evaluation of a portable ketometer for on-site monitoring of blood β-hydroxybutyrate concentrations in dairy sheep and goats;Panousis;Rev. Med. Vet. (Toulouse),2018
3. Pregnancy Toxemia of Ewes, Does, and Beef Cows
4. Studies on clinical signs and biochemical alteration in pregnancy toxemic goats
5. Pregnancy impairs ketone body disposal in late gestating ewes: Implications for onset of pregnancy toxaemia
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