Amazon Rainforest Hidden Volatiles—Part I: Unveiling New Compounds from Acmella oleracea (L.) R.K. Jansen Essential Oil-Reference-Cited by-同舟云学术

Amazon Rainforest Hidden Volatiles—Part I: Unveiling New Compounds from Acmella oleracea (L.) R.K. Jansen Essential Oil

Published:2024-06-19 Issue:12 Volume:13 Page:1690
ISSN:2223-7747
Container-title:Plants
language:en
Short-container-title:Plants

Author:

Radulović Niko S.¹^ORCID,Mladenović Marko Z.¹^ORCID,Lima Clarissa Silva²³^ORCID,Müller Elza Caroline Alves²,da Costa Elizabeth Vianna Moraes²,Martins Rozilene Valadares³,Boylan Fabio⁴^ORCID

Affiliation:

1. Department of Chemistry, Faculty of Sciences and Mathematics, University of Niš, Višegradska 33, 18000 Niš, Serbia

2. Department of Biological Sciences and Health, Federal University of Amapá, Highway Juscelino Kubitschek, Km 02, Macapá 68903-197, Brazil

3. Postgraduate Program in Health Sciences, Federal University of Amapá, Highway Juscelino Kubitschek, Km 02, Macapá 68903-197, Brazil

4. School of Pharmacy and Pharmaceutical Sciences, Panoz Institute, and Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, D02 PN40 Dublin, Ireland

Abstract

Motivated by the culinary and ethnopharmacological use of Acmella oleracea (L.) R.K. Jansen, this study aimed to unveil new chemical compounds from its essential oil (EO). Acmella oleracea, known for its anesthetic and spicy properties, has been used in traditional medicine and cuisine, particularly in Northern Brazil. Through a detailed GC-MS analysis, 180 constituents were identified, including 12 tentatively identified long-chain α-keto esters of various acids. Additionally, 18 new esters were synthesized for structural verification. This research expands the known chemical diversity of A. oleracea EO, providing a basis for potential pharmacological applications. The identification of new natural products, including homologs and analogs of acmellonate, underscores the EO’s rich chemical profile and its potential for novel bioproduct development.

Funder

Ministry of Science, Technological Development, and Innovation of the Republic of Serbia

Brazilian National Council for Scientific and Technological Development CNPq/FAPEAP/PRONEM

Publisher

MDPI AG

Link

https://www.mdpi.com/2223-7747/13/12/1690/pdf

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