A 14-3-3 Protein Ca16R Acts Positively in Pepper Immunity against Ralstonia solanacearum by Interacting with CaASR1

Author:

Yang Sheng1,Wan Meiyun2,Cheng Xingge2,Cheng Qing1ORCID,Shen Huolin1

Affiliation:

1. Department of Vegetable Science, College of Horticulture, China Agricultural University, Beijing 100193, China

2. College of Agriculture, Fujian Agriculture and Forestry University, Fuzhou 350002, China

Abstract

Although 14-3-3 proteins have been implicated in plant growth, development, and stress response, their roles in pepper immunity against R. solanacearum remain poorly understood. In this study, a 14-3-3-encoding gene in pepper, Ca16R, was found to be upregulated by R. solanacearum inoculation (RSI), its silencing significantly reduced the resistance of pepper plants to RSI, and its overexpression significantly enhanced the resistance of Nicotiana benthamiana to RSI. Consistently, its transient overexpression in pepper leaves triggered HR cell death, indicating that it acts positively in pepper immunity against RSI, and it was further found to act positively in pepper immunity against RSI by promoting SA but repressing JA signaling. Ca16R was also found to interact with CaASR1, originally using pull-down combined with a spectrum assay, and then confirmed using bimolecular fluorescence complementation (BiFC) and a pull-down assay. Furthermore, we found that CaASR1 transient overexpression induced HR cell death and SA-dependent immunity while repressing JA signaling, although this induction and repression was blocked by Ca16R silencing. All these data indicate that Ca16R acts positively in pepper immunity against RSI by interacting with CaASR1, thereby promoting SA-mediated immunity while repressing JA signaling. These results provide new insight into mechanisms underlying pepper immunity against RSI.

Funder

Beijing Joint Research Program for Germplasm Innovation and New Variety Breeding

Major Science and Technology plan of Hainan Province

National Natural Science Foundation of China

Construction of Beijing Science and Technology Innovation and Service Capacity in Top Subjects

Publisher

MDPI AG

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