The Systematic Assessment of the Membrane-Stabilizing and Antioxidant Activities of Several Kazakhstani Plants in the Asteraceae Family
Author:
Ydyrys Alibek123ORCID, Zhamanbayeva Gulzhan23, Zhaparkulova Nazgul23, Aralbaeva Arailym4, Askerbay Gulnaz2, Kenzheyeva Zhanar2, Tussupbekova Gulmira2, Syraiyl Sayagul2, Kaparbay Raushan123, Murzakhmetova Maira2
Affiliation:
1. Biomedical Research Centre, Al-Farabi Kazakh National University, al-Farabi Av. 71, Almaty 050040, Kazakhstan 2. Department of Biophysics, Biomedicine and Neuroscience, Al-Farabi Kazakh National University, al-Farabi Av. 71, Almaty 050040, Kazakhstan 3. Scientific Research Institute for Issues in Biology and Biotechnology, Al-Farabi Kazakh National University, Al-Farabi Ave. 71, Almaty 050040, Kazakhstan 4. Faculty of Medicine and Health Care, Al-Farabi Kazakh National University, al-Farabi Av. 71, Almaty 050040, Kazakhstan
Abstract
The objective of our research was to examine the antioxidant and membrane-protective characteristics of a few medicinal plant extracts belonging to the Asteracea family, along with their flavonoid and polyphenolic content, in order to identify strategies for enhancing beverage composition and boosting the antioxidant capacity of green and black tea. The activity of aqueous-ethanolic extracts from the dried parts of plants, such as Arictum tomentosum Mill., Ghnapilum kasachstanicum Kirp. & Kuprian. ex Kirp., Artemisia schrenkiana Ledeb., A. rutifolia Steph. ex Spreng., A. cina O.Berg, and A. vulgaris L., were examined using a model of Wistar rats. Thiobarbituric acid-reacting substances (TBARS), a marker of malondialdehyde concentration, were used to measure the amount of lipid peroxidation (LPO) in liver microsomes. Considering the outcomes, the extracts from A. tomentosum, G. kasachstanicum, and A. vulgaris exhibit the strongest membrane-stabilizing action among those examined. At a concentration of 5 g/mL, the extracts of these plants demonstrated a significant anti-hemolitic impact, whereas the remaining extracts displayed a similar effect at doses above 10 g/mL. Accordingly, among the extracts studied, the A. tomentosum, G. kasachstanicum, A. schrenkiana, A. rutifolia, A. cina, and A. vulgaris extracts have significant antioxidant properties. The integrated antioxidant and antihemolytic qualities of A. tomentosum and green tea extracts were comparable to those of the individual plant extracts. When the extracts of A. schrenkiana and green tea were combined, similar outcomes were seen, suggesting that there was no appreciable synergistic interaction.
Funder
Scientific Committee of the Ministry of Science and Higher Education of the Republic of Kazakhstan
Subject
Plant Science,Ecology,Ecology, Evolution, Behavior and Systematics
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