Affiliation:
1. Department of Applied Mechanics, Vilnius Gediminas Technical University, LT-10223 Vilnius, Lithuania
Abstract
An evaluation of the impact of osteoporosis on loss of spinal stability, with or without intervertebral disc degeneration, using computational analysis is presented. The research also investigates the correlation between osteoporosis and intervertebral disc degeneration. Three-dimensional finite element models of human lumbar spine segments were used to assess the influence of osteoporosis on spinal stability. Five different models of age-related degeneration were created using various material properties for trabecular bone and intervertebral discs. Calculation results indicate that in a spine with osteoporosis, the deformation of the intervertebral discs can increase by more than 30% when compared to a healthy spine. Thus, intervertebral disc deformation depends not only on the degree of degeneration of the discs themselves, but their deformation is also influenced by the degree of osteoporosis of the vertebrae. Additionally, the load-bearing capacity of the spine can decrease by up to 30% with osteoporosis, regardless of the degree of intervertebral disc deformation. In conclusion, osteoporosis can contribute to intervertebral disc degeneration.
Reference53 articles.
1. Adult Spinal Deformity: Current Concepts and Decision-Making Strategies for Management;Kim;Asian Spine J.,2020
2. Zhang, Q., Chon, T., Zhang, Y., Baker, J.S., and Gu, Y. (2021). Finite Element Analysis of the Lumbar Spine in Adolescent Idiopathic Scoliosis Subjected to Different Loads. Comput. Biol. Med., 136.
3. Argirò, R., Diacinti, D., Sacconi, B., Iannarelli, A., D’Adamo, E.A., Sandolo, F., Bezzi, M., and Catalano, C. (2013, January 7–11). MRI Assessment of Vertebral Fractures Identified by Conventional Radiography in Osteoporotic Patients: A Preliminary Study. Proceedings of the European Congress of Radiology—ECR 2013, Vienna, Austria.
4. Density and Mechanical Properties of Vertebral Trabecular Bone—A Review;Holub;JOR Spine,2021
5. Spinal Biomechanics-Biomechanical Considerations of Spinal Stability in the Context of Spinal Injury;Loughenbury;Orthop. Trauma,2016